A0M5M5 (A0M5M5_GRAFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Degradative hydroxymethylglutaryl-CoA reductase EMBL CAL67920.1
EC=1.1.1.88 EMBL CAL67920.1

Gene names

Name:	hmgA EMBL CAL67920.1
Ordered Locus Names:	GFO_2973

Organism

Gramella forsetii (strain KT0803) [Complete proteome] [HAMAP]

Taxonomic identifier

411154 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length	437 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAL67920.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0M5M5 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: DDD0A1581BD0276C	FASTA	437	49,055
	10 20 30 40 50 60 MTKPVNGFSK FSKSEKIAWL AENYLAENKK AVSTLQQYWN DDEKLQKLHD EFIENTVSNF 70 80 90 100 110 120 YLPLGLAPNF LINGKHHVLP MAIEESSVVA AASKAAKFWS ERGGFKATVI NQKKIGQVHF 130 140 150 160 170 180 LYTGDFSKLE KLFKNIEPKF RESVKSITRN MEKRGGGILE IDLIDKTQDL KNYYQLFVKF 190 200 210 220 230 240 DTRDSMGANF INSCLEKFAE VLQEEASKVQ DFTKEENLQI IMSILSNYVP ECIVRAEVSC 250 260 270 280 290 300 PVNELSEDKN MSGEQFAEKF VQAVKIAEIE PYRAVTHNKG IMNGIDAVVL ATGNDFRAVE 310 320 330 340 350 360 AGIHAYASRN GSYSSLTHAS VENGIFKFWM EIPLALGTVG GLTSLHPLVK LALDILQKPS 370 380 390 400 410 420 ASELMEITAV AGLAQNFAAL RSLTTTGIQQ GHMKMHLMNI LNQNEATENE KEKMVEYFTH 430 HTITHSSVID QLEKIRS

References

[1]

"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter." Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O. Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207366 Genomic DNA. Translation: CAL67920.1.
RefSeq	YP_862987.1. NC_008571.1.
3D structure databases
ProteinModelPortal	A0M5M5.
ModBase	Search...
Protein-protein interaction databases
STRING	A0M5M5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4651094.
GenomeReviews	Gene locus GFO_2973 in contig CU207366_GR.
KEGG	gfo:GFO_2973.
NMPDR	fig|411154.5.peg.2806.
PATRIC	22074694. VBIGraFor5527_2866.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1257.
HOGENOM	HBG477902.
OMA	NNKGIMN.
ProtClustDB	CLSK851767.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0M5M5_GRAFK

Accession

Primary (citable) accession number: A0M5M5

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)