A0M5L6 (SURE_GRAFK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	GFO_2964

Organism

Gramella forsetii (strain KT0803) [Complete proteome] [HAMAP]

Taxonomic identifier

411154 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 260	260	5'-nucleotidase surE HAMAP MF_00060		PRO_1000007732
Sites
	Metal binding	13	1	Divalent metal cation By similarity
	Metal binding	14	1	Divalent metal cation By similarity
	Metal binding	44	1	Divalent metal cation By similarity
	Metal binding	102	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0M5L6 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 3A2F1A4217590654	FASTA	260	28,665
	10 20 30 40 50 60 MNKKKPLILV TNDDGITAPG IRTLVEVMKE LGDVIVVAPD SPQSGMGHAI TISDTLFCEQ 70 80 90 100 110 120 VTIKESYKHK EYSCSGTPAD CVKIATQEIL HRKPDLCVSG INHGSNSSIN VIYSGTMSAA 130 140 150 160 170 180 VEAGIEGIPA IGFSLLDYSL NADFEPTRKF IKTITKNVLK NGLPIGVVLN VNIPKLKEAE 190 200 210 220 230 240 IKGIKVCRQA NAHWEEEFDK RTNPQGREYY WLTGKFVNKD EGKDTDEKAL EEGYVSVVPV 250 260 QFDLTAHHFI KDLSSWSLND

References

[1]

"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter." Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O. Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KT0803.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207366 Genomic DNA. Translation: CAL67911.1.
RefSeq	YP_862978.1. NC_008571.1.
3D structure databases
ProteinModelPortal	A0M5L6.
ModBase	Search...
Protein-protein interaction databases
STRING	A0M5L6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4651087.
GenomeReviews	Gene locus GFO_2964 in contig CU207366_GR.
KEGG	gfo:GFO_2964.
NMPDR	fig|411154.5.peg.2797.
PATRIC	22074676. VBIGraFor5527_2857.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	SINVIYS.
PhylomeDB	A0M5L6.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	GFOR411154:GFO_2964-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_GRAFK

Accession

Primary (citable) accession number: A0M5L6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program