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Protein

Dihydrolipoyl dehydrogenase

Gene

lpd

Organism
Gramella forsetii (strain KT0803)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Miscellaneous

The active site is a redox-active disulfide bond.UniRule annotation

Catalytic activityi

Protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandFADUniRule annotation, Flavoprotein, NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoyl dehydrogenaseUniRule annotation (EC:1.8.1.4UniRule annotation)
Gene namesi
Name:lpdImported
Ordered Locus Names:GFO_2165Imported
OrganismiGramella forsetii (strain KT0803)Imported
Taxonomic identifieri411154 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeGramella
Proteomesi
  • UP000000755 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi411154.GFO_2165.

Structurei

3D structure databases

ProteinModelPortaliA0M3D5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 328FAD/NAD-binding_domInterPro annotationAdd BLAST325
Domaini347 – 456Pyr_redox_dimInterPro annotationAdd BLAST110

Sequence similaritiesi

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4107QN2. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276708.
KOiK00382.
OMAiCIDEWKN.
OrthoDBiPOG091H0239.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
InterProiView protein in InterPro
IPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006258. Lipoamide_DH.
IPR001100. Pyr_nuc-diS_OxRdtase.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR012999. Pyr_OxRdtase_I_AS.
PfamiView protein in Pfam
PF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
PIRSFiPIRSF000350. Mercury_reductase_MerA. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.
PROSITEiView protein in PROSITE
PS00076. PYRIDINE_REDOX_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A0M3D5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTYDVAVIG SGPGGYVAAI RCAQLGMKTA IIEKYSTLGG TCLNVGCIPS
60 70 80 90 100
KALLDSSHHY DDAIKHFEDH GIEIPGEVKL NLEKMMERKS SVVSQTCDGV
110 120 130 140 150
KFLMDKNKID VIEGVGSFKD KTHINIEKDG ETQTIEAKKT IIATGSKPAN
160 170 180 190 200
LPFIELDKER VITSTEALTL KEVPKHMIVI GGGVIGLELG QVYRRLGAEV
210 220 230 240 250
TVVEFMDRII PTMDSALSKE LQKVLKKQGV KFHTSTKVKS VERNGDEITI
260 270 280 290 300
KADDKKDKEI ELKGDYCLVS VGRRPFTDGL NAEAAGVKLD DKGRVKVNDH
310 320 330 340 350
LQTNVENIYA IGDVVRGAML AHKAEEEGSM VAELMAGQKP HIDYNLIPGV
360 370 380 390 400
VYTWPEVASV GKTEEQLKEE GVKYKEGKFP MRALGRSRAS GDIDGLVKIL
410 420 430 440 450
ADEKTDEVLG VHMIGARTAD LIAEAVTAME FRASAEDIAR MSHAHPTYAE
460
AVKEAALAAT ENRALHI
Length:467
Mass (Da):50,839
Last modified:December 12, 2006 - v1
Checksum:i21169A874FF51F3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207366 Genomic DNA. Translation: CAL67130.1.
RefSeqiWP_011710033.1. NC_008571.1.

Genome annotation databases

EnsemblBacteriaiCAL67130; CAL67130; GFO_2165.
KEGGigfo:GFO_2165.

Similar proteinsi

Entry informationi

Entry nameiA0M3D5_GRAFK
AccessioniPrimary (citable) accession number: A0M3D5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: September 27, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported