A0M369 (A0M369_GRAFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP MF_00006
Short name=ASAL HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006

Alternative name(s):
Arginosuccinase HAMAP MF_00006

Gene names

Name:	argH HAMAP MF_00006 EMBL CAL67064.1
Ordered Locus Names:	GFO_2099

Organism

Gramella forsetii (strain KT0803) [Complete proteome] [HAMAP]

Taxonomic identifier

411154 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length	429 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006
Subcellular location	Cytoplasm By similarity HAMAP MF_00006.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00006
Cellular component	Cytoplasm HAMAP MF_00006
Molecular function	Lyase HAMAP MF_00006 EMBL CAL67064.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0M369 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: B6D270BB3E5B69D4	FASTA	429	48,771
	10 20 30 40 50 60 MKLWDKGISI DKQIEKFTVG NDRELDMHLA EYDIQASKAH AKMLGKVGIL EKDEVETILT 70 80 90 100 110 120 ELEVLKKQLE NGLFHIEEDF EDVHSKIEFE LTKKLGDTGK KIHTARSRND QVLVAQQLYF 130 140 150 160 170 180 KENLQQISEK AKELIEVLLG LADEHKEKLL PGYTHLQVAM PSSFGLWFSA YAELLIDDLY 190 200 210 220 230 240 LLEAGLKIVD QNPLGSAAGY GSSFPIDREF TTRELGFSTQ KFNVVAAQMS RGKCERTVTS 250 260 270 280 290 300 NIASLANTLS RLAMDICLYM SQNFDFITFP DELTTGSSIM PHKKNPDVFE LVRGKCNKLQ 310 320 330 340 350 360 AIANEMILIT NNLPSGYHRD FQLIKENSIY SVENMKEILD VFTHSIAQIK VKNVDLKDEK 370 380 390 400 410 420 YKYLFTVDSI NELVINGKSF RDAYKIIGEQ VQDGSYKATE GMQHSHSGSK DNLSLEKIRE KKEEINLKI

References

[1]

"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter." Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O. Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207366 Genomic DNA. Translation: CAL67064.1.
RefSeq	YP_862131.1. NC_008571.1.
3D structure databases
ProteinModelPortal	A0M369.
ModBase	Search...
Protein-protein interaction databases
STRING	A0M369.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4652594.
GenomeReviews	Gene locus GFO_2099 in contig CU207366_GR.
KEGG	gfo:GFO_2099.
NMPDR	fig|411154.5.peg.1988.
PATRIC	22072973. VBIGraFor5527_2024.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0165.
HOGENOM	HBG539632.
OMA	KKNPDVF.
ProtClustDB	PRK00855.
Family and domain databases
HAMAP	MF_00006. Arg_succ_lyase. [Tree]
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR008948. L-Aspartase-like. IPR022761. Lyase1_N. [Graphical view]
KO	K01755.
PANTHER	PTHR11444:SF3. argH. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. ArgH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0M369_GRAFK

Accession

Primary (citable) accession number: A0M369

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)