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Protein

Dihydrolipoyl dehydrogenase

Gene

lpd

Organism
Gramella forsetii (strain KT0803)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

FADUniRule annotation, Flavoprotein, NADUniRule annotation

Enzyme and pathway databases

BioCyciGFOR411154:GI79-1865-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoyl dehydrogenaseUniRule annotation (EC:1.8.1.4UniRule annotation)
Gene namesi
Name:lpdImported
Ordered Locus Names:GFO_1865Imported
OrganismiGramella forsetii (strain KT0803)Imported
Taxonomic identifieri411154 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeGramella
Proteomesi
  • UP000000755 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi411154.GFO_1865.

Structurei

3D structure databases

ProteinModelPortaliA0M2J0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 324321FAD/NAD-binding_domInterPro annotationAdd
BLAST
Domaini344 – 452109Pyr_redox_dimInterPro annotationAdd
BLAST

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4107QN2. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276708.
KOiK00382.
OMAiYRQAMNL.
OrthoDBiPOG091H0239.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006258. Lipoamide_DH.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR012999. Pyr_OxRdtase_I_AS.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.
PROSITEiPS00076. PYRIDINE_REDOX_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0M2J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKYDIIVLG SGPGGYVTAI RASQLGFKTA IVEKESLGGV CLNWGCIPTK
60 70 80 90 100
ALLKSAEVFD YLKHAEDYGL KLEKADKDFG AVVKRSRDVA DGMSKGVQFL
110 120 130 140 150
MKKNKIDVLE GFGKLKSGKK VEVTDSKDKK TEYQADNVII ATGARSRELP
160 170 180 190 200
NLKQDGKTVI GYREAMTLKK QPKSMIVVGS GAIGVEFAHF YNAMGTEVTV
210 220 230 240 250
VEYLPNVVPL EDEEVSKQFE RSIKKAGIKV MTNSSVESVE KSGGKVKAKV
260 270 280 290 300
KTKKGEETLE ADIVLSAVGI KSNIENIGLE DLNIKTEKDK IVVNDFYQTN
310 320 330 340 350
VSGIYAIGDV VHGPALAHVA SAEGILCVEK IKGMDVEPLD YGNIPGCTYA
360 370 380 390 400
TPEIASVGMT EKQAKEAGYE LKIGKFPFSA SGKASASGKK DGFVKVIFDA
410 420 430 440 450
KYGEWLGCHM IGAGVTDMIA EAVLGRKLET TGHEVLKAVH PHPTMSEAVM
460
EAVAAAYDEV IHL
Length:463
Mass (Da):49,823
Last modified:December 12, 2006 - v1
Checksum:i4A059F5F5D0620E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207366 Genomic DNA. Translation: CAL66835.1.
RefSeqiWP_011709743.1. NC_008571.1.

Genome annotation databases

EnsemblBacteriaiCAL66835; CAL66835; GFO_1865.
KEGGigfo:GFO_1865.
PATRICi22072517. VBIGraFor5527_1801.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207366 Genomic DNA. Translation: CAL66835.1.
RefSeqiWP_011709743.1. NC_008571.1.

3D structure databases

ProteinModelPortaliA0M2J0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi411154.GFO_1865.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL66835; CAL66835; GFO_1865.
KEGGigfo:GFO_1865.
PATRICi22072517. VBIGraFor5527_1801.

Phylogenomic databases

eggNOGiENOG4107QN2. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276708.
KOiK00382.
OMAiYRQAMNL.
OrthoDBiPOG091H0239.

Enzyme and pathway databases

BioCyciGFOR411154:GI79-1865-MONOMER.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006258. Lipoamide_DH.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR012999. Pyr_OxRdtase_I_AS.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.
PROSITEiPS00076. PYRIDINE_REDOX_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0M2J0_GRAFK
AccessioniPrimary (citable) accession number: A0M2J0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: September 7, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The active site is a redox-active disulfide bond.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.