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Protein

Ribosomal RNA large subunit methyltransferase H

Gene

rlmH

Organism
Gramella forsetii (strain KT0803)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + pseudouridine(1915) in 23S rRNA = S-adenosyl-L-homocysteine + N(3)-methylpseudouridine(1915) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciGFOR411154:GI79-1101-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase HUniRule annotation (EC:2.1.1.177UniRule annotation)
Alternative name(s):
23S rRNA (pseudouridine1915-N3)-methyltransferaseUniRule annotation
23S rRNA m3Psi1915 methyltransferaseUniRule annotation
rRNA (pseudouridine-N3-)-methyltransferase RlmHUniRule annotation
Gene namesi
Name:rlmHUniRule annotation
Ordered Locus Names:GFO_1101
OrganismiGramella forsetii (strain KT0803)
Taxonomic identifieri411154 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeGramella
Proteomesi
  • UP000000755 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 157157Ribosomal RNA large subunit methyltransferase HPRO_1000061786Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi411154.GFO_1101.

Structurei

3D structure databases

ProteinModelPortaliA0M0D0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA methyltransferase RlmH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UXA. Bacteria.
COG1576. LUCA.
HOGENOMiHOG000218433.
KOiK00783.
OMAiYCEIEIK.
OrthoDBiEOG6S26HR.

Family and domain databases

Gene3Di3.40.1280.10. 1 hit.
HAMAPiMF_00658. 23SrRNA_methyltr_H.
InterProiIPR029028. Alpha/beta_knot_MTases.
IPR003742. SPOUT_MeTrfase.
IPR029026. tRNA_m1G_MTases_N.
[Graphical view]
PfamiPF02590. SPOUT_MTase. 1 hit.
[Graphical view]
PIRSFiPIRSF004505. MT_bac. 1 hit.
SUPFAMiSSF75217. SSF75217. 1 hit.

Sequencei

Sequence statusi: Complete.

A0M0D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIKLVCIGK TDKKELEALI KIYSDRLQHY IKFEFEIIPD LKKTKNLDEN
60 70 80 90 100
QQKSKEGELI LSGVQNSDFV VLLDENGKQF SSESFSEYIQ KRMNTGLKRL
110 120 130 140 150
IFVIGGPYGF SEEVYKRADS KISLSKMTFS HQMVRLFFTE QLYRAFTILK

NEPYHHR
Length:157
Mass (Da):18,455
Last modified:December 12, 2006 - v1
Checksum:iA3A7CA788E534E04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207366 Genomic DNA. Translation: CAL66075.1.
RefSeqiWP_011708994.1. NC_008571.1.

Genome annotation databases

EnsemblBacteriaiCAL66075; CAL66075; GFO_1101.
KEGGigfo:GFO_1101.
PATRICi22071029. VBIGraFor5527_1061.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207366 Genomic DNA. Translation: CAL66075.1.
RefSeqiWP_011708994.1. NC_008571.1.

3D structure databases

ProteinModelPortaliA0M0D0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi411154.GFO_1101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL66075; CAL66075; GFO_1101.
KEGGigfo:GFO_1101.
PATRICi22071029. VBIGraFor5527_1061.

Phylogenomic databases

eggNOGiENOG4108UXA. Bacteria.
COG1576. LUCA.
HOGENOMiHOG000218433.
KOiK00783.
OMAiYCEIEIK.
OrthoDBiEOG6S26HR.

Enzyme and pathway databases

BioCyciGFOR411154:GI79-1101-MONOMER.

Family and domain databases

Gene3Di3.40.1280.10. 1 hit.
HAMAPiMF_00658. 23SrRNA_methyltr_H.
InterProiIPR029028. Alpha/beta_knot_MTases.
IPR003742. SPOUT_MeTrfase.
IPR029026. tRNA_m1G_MTases_N.
[Graphical view]
PfamiPF02590. SPOUT_MTase. 1 hit.
[Graphical view]
PIRSFiPIRSF004505. MT_bac. 1 hit.
SUPFAMiSSF75217. SSF75217. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter."
    Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O.
    Environ. Microbiol. 8:2201-2213(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KT0803.

Entry informationi

Entry nameiRLMH_GRAFK
AccessioniPrimary (citable) accession number: A0M0D0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 12, 2006
Last modified: November 11, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.