A0LZ13 (A0LZ13_GRAFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377 EMBL CAL65608.1
Ordered Locus Names:	GFO_0630

Organism

Gramella forsetii (strain KT0803) [Complete proteome] [HAMAP]

Taxonomic identifier

411154 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377 RuleBase RU000577
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 RuleBase RU000577 DNA-binding HAMAP MF_00377 RuleBase RU000577 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	180 – 187	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	A0LZ13 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 6591049FBDEF010B	FASTA	475	54,128
	10 20 30 40 50 60 MSKTAQSVWN NCLSFIQDNI TPQAYKTWFE PIQAVKLTDC ALSIQVPSKF FYEWLEEHYV 70 80 90 100 110 120 KLLKVSLTRE LGEKAKLVYV IKMENTYGNK LPFTEKIPST QRAQMTSQEV DVPIKNKSPE 130 140 150 160 170 180 LKNPFIIPGI RNVKIESQLN PNYNFDNFLE GESNRLARSA GLAVANKPGG TSFNPLLIFG 190 200 210 220 230 240 GVGLGKTHLA HAIGVEIKDK YPEKTVLYIS AEKFTQQYIE SVKKNNRNDF IHFYQIIDVL 250 260 270 280 290 300 VVDDIQLLSG KAGTQDVFFH IFNHLHQNGK QVILTSDKAP VDMQDIEQRL LSRFKWGLSA 310 320 330 340 350 360 ELQHPDFETR VSIIKSKLYR DGVEMPEDIV EFLANNIKTN IRELEGAIIS LIAHSSFNKK 370 380 390 400 410 420 DITLDLAKKI VDNYVKNTKR EVSIDYIQKV VSDYFQMDVD TLQSKTRKRH IVQARQLAMF 430 440 450 460 470 FAKKFTKASL ASIGSQIGSR DHATVLHACK TVDNLASTDK QFKKFVEDLS KKLTL

References

[1]

"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter." Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O. Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207366 Genomic DNA. Translation: CAL65608.1.
RefSeq	YP_860675.1. NC_008571.1.
3D structure databases
ProteinModelPortal	A0LZ13.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LZ13.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4651846.
GenomeReviews	Gene locus GFO_0630 in contig CU207366_GR.
KEGG	gfo:GFO_0630.
NMPDR	fig|411154.5.peg.594.
PATRIC	22070111. VBIGraFor5527_0606.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0593.
HOGENOM	HBG695666.
OMA	CHTLNAL.
PhylomeDB	A0LZ13.
ProtClustDB	PRK00149.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0LZ13_GRAFK

Accession

Primary (citable) accession number: A0LZ13

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)