A0LY37 (A0LY37_GRAFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209

Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209

Gene names

Name:	ppa HAMAP MF_00209 EMBL CAL65282.1
Ordered Locus Names:	GFO_0296

Organism

Gramella forsetii (strain KT0803) [Complete proteome] [HAMAP]

Taxonomic identifier

411154 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length	170 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Diphosphate + H2O = 2 phosphate. HAMAP MF_00209
Cofactor	Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209
Subcellular location	Cytoplasm By similarity HAMAP MF_00209.
Sequence similarities	Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00209
Ligand	Magnesium HAMAP MF_00209 Metal-binding HAMAP MF_00209
Molecular function	Hydrolase HAMAP MF_00209 EMBL CAL65282.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphate-containing compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	inorganic diphosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	54	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	59	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	59	1	Magnesium 2 By similarity HAMAP MF_00209
	Metal binding	91	1	Magnesium 1 By similarity HAMAP MF_00209

Sequences

	Sequence		Length	Mass (Da)
	A0LY37 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 31A56C4EDEF31BEB	FASTA	170	19,781
	10 20 30 40 50 60 MSDTFDVLIE IPKGSRNKYE YDFELKKVRY DRMIFSSMMY PADYGFIPNT LALDEDPLDV 70 80 90 100 110 120 LVLVSEPTFP GIVMEVKPIG VFHMADEKGP DEKIICVPVS DPIWNRLNDL KELNGHMIKE 130 140 150 160 170 IEHFFKVYKD LEKKKVDTGD FGDANEAREI IRQCVERFEN YEGDKSRFGI

References

[1]

"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter." Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O. Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207366 Genomic DNA. Translation: CAL65282.1.
RefSeq	YP_860352.1. NC_008571.1.
3D structure databases
ProteinModelPortal	A0LY37.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LY37.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4651083.
GenomeReviews	Gene locus GFO_0296 in contig CU207366_GR.
KEGG	gfo:GFO_0296.
NMPDR	fig|411154.5.peg.279.
PATRIC	22069463. VBIGraFor5527_0290.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0221.
HOGENOM	HBG529150.
OMA	PNDFNVI.
PhylomeDB	A0LY37.
ProtClustDB	CLSK851274.
Family and domain databases
HAMAP	MF_00209. Inorganic_PPase. [Tree]
InterPro	IPR008162. Pyrophosphatase. [Graphical view]
Gene3D	G3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KO	K01507.
PANTHER	PTHR10286. Pyrophosphatase. 1 hit.
Pfam	PF00719. Pyrophosphatase. 1 hit. [Graphical view]
SUPFAM	SSF50324. Pyrophosphatase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0LY37_GRAFK

Accession

Primary (citable) accession number: A0LY37

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)