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Protein
Submitted name:

Secreted protein containing adenylate/guanylate cyclase catalytic domain

Gene

GFO_0018

Organism
Gramella forsetii (strain KT0803)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Enzyme and pathway databases

BioCyciGFOR411154:GI79-18-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Secreted protein containing adenylate/guanylate cyclase catalytic domainImported (EC:4.6.1.-Imported)
Gene namesi
Ordered Locus Names:GFO_0018Imported
OrganismiGramella forsetii (strain KT0803)Imported
Taxonomic identifieri411154 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeGramella
Proteomesi
  • UP000000755 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei354 – 37421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi411154.GFO_0018.

Structurei

3D structure databases

ProteinModelPortaliA0LXB4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini87 – 237151TPR_REGIONInterPro annotationAdd
BLAST
Domaini284 – 31734TPR_REGIONInterPro annotationAdd
BLAST
Domaini425 – 555131Guanylate cyclaseInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili217 – 24024Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatUniRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4107Y20. Bacteria.
COG2114. LUCA.
OMAiNISENTY.
OrthoDBiEOG6C012M.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00515. TPR_1. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00028. TPR. 5 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 2 hits.
SSF55073. SSF55073. 1 hit.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50005. TPR. 5 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0LXB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIHLLKYRT FLFLLLFLVN SVNKGFSQNQ TKADSLEKIY NSSSRARQNL
60 70 80 90 100
EILKDLSENS IAPYMKLKFS EELLEIAKKR NSQSYFYTGY LQKGNALASR
110 120 130 140 150
GDFTEALESY FQAASVAKNE KELGLIKVTL GDVYSLTKNH QRSLNYYNEA
160 170 180 190 200
IEIFRKTKDS LTLGSVIFNA GDGYLKNNQM DMAISYLEES EQIFKNINFD
210 220 230 240 250
LGLAYCSGTL GLAYAKLGRN EEAEKNIQQA IQALEKAEDY SPICEFLNGM
260 270 280 290 300
ADIYTEKNED STAIEFASIS RDLARTYGFK NETREANLRL AQIYEKTGNI
310 320 330 340 350
PEAYKFYKEY IIYRDSVLNV STAQNMAGLR ADYEVAQKQI EVDLLSAQRE
360 370 380 390 400
NQQLVVISIA VASFLVCLLA FGLYRRNRFI KRTSAIIEKE KNRSELLLLN
410 420 430 440 450
ILPEETAREL KKNGKVRAKK FESVTVLFAD FKRFTLIAEN LPPERLIKTI
460 470 480 490 500
DYYFSQFDKI MEKYDIEKIK TIGDSYMAAS GLPFPNQDHA YKILMAAFEM
510 520 530 540 550
TQFVKETKEN SLYDDANFDV RVGLNSGPVV AGVVGTKKFA YDIWGDTVNI
560 570 580 590 600
AARMESHSDI GKINISENTY DLIKDKFDCE YRGEVEVKNG RILKMYYVKD
610
IKEEENKIAG
Length:610
Mass (Da):69,795
Last modified:December 12, 2006 - v1
Checksum:i4954A151C7849AE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207366 Genomic DNA. Translation: CAL65009.1.
RefSeqiWP_011707947.1. NC_008571.1.

Genome annotation databases

EnsemblBacteriaiCAL65009; CAL65009; GFO_0018.
KEGGigfo:GFO_0018.
PATRICi22068909. VBIGraFor5527_0018.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207366 Genomic DNA. Translation: CAL65009.1.
RefSeqiWP_011707947.1. NC_008571.1.

3D structure databases

ProteinModelPortaliA0LXB4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi411154.GFO_0018.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL65009; CAL65009; GFO_0018.
KEGGigfo:GFO_0018.
PATRICi22068909. VBIGraFor5527_0018.

Phylogenomic databases

eggNOGiENOG4107Y20. Bacteria.
COG2114. LUCA.
OMAiNISENTY.
OrthoDBiEOG6C012M.

Enzyme and pathway databases

BioCyciGFOR411154:GI79-18-MONOMER.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00515. TPR_1. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00028. TPR. 5 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 2 hits.
SSF55073. SSF55073. 1 hit.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50005. TPR. 5 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter."
    Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O.
    Environ. Microbiol. 8:2201-2213(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KT0803Imported.

Entry informationi

Entry nameiA0LXB4_GRAFK
AccessioniPrimary (citable) accession number: A0LXB4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: March 16, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.