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Protein

Chaperone protein ClpB

Gene

clpB

Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation
Biological processStress responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein ClpBUniRule annotation
Gene namesi
Name:clpBUniRule annotation
Ordered Locus Names:Acel_2119Imported
OrganismiAcidothermus cellulolyticus (strain ATCC 43068 / 11B)Imported
Taxonomic identifieri351607 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidothermalesAcidothermaceaeAcidothermus
Proteomesi
  • UP000008221 Componenti: Chromosome

Subcellular locationi

A0LWT1:
  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homohexamer. The oligomerization is ATP-dependent.SAAS annotation
Homohexamer; The oligomerization is ATP-dependent.UniRule annotation

Protein-protein interaction databases

STRINGi351607.Acel_2119.

Structurei

3D structure databases

ProteinModelPortaliA0LWT1.
SMRiA0LWT1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini199 – 340AAAInterPro annotationAdd BLAST142
Domaini599 – 748AAAInterPro annotationAdd BLAST150
Domaini766 – 857ClpB_D2-smallInterPro annotationAdd BLAST92

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili439 – 493UniRule annotationAdd BLAST55

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilUniRule annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C2Z. Bacteria.
COG0542. LUCA.
HOGENOMiHOG000218209.
KOiK03695.
OMAiHHKVRIK.
OrthoDBiPOG091H019M.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR017730. Chaperonin_ClpB.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR036628. Clp_N_dom_sf.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 2 hits.
PF10431. ClpB_D2-small. 1 hit.
PRINTSiPR00300. CLPPROTEASEA.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF81923. SSF81923. 1 hit.
TIGRFAMsiTIGR03346. chaperone_ClpB. 1 hit.
PROSITEiView protein in PROSITE
PS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0LWT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGYRLTTKS QEALNQAVHA AAEAGHPHVE PAHLLMALLQ QSDGTALPLL
60 70 80 90 100
RAVGVNPVAL QGDVREILDR LPRASGATVA PPGLDRPSIQ VLNAAAKEAA
110 120 130 140 150
ELGDEYVSTE HLLVGLAREG GAVAALLRRH GATPENLLAA FERVRGHARV
160 170 180 190 200
TSPDPESTYQ ALEKYGVDLT ERARKGQLDP IIGRDTEIRR VIQVLSRRTK
210 220 230 240 250
NNPVLIGEPG VGKTAIVEGL AQRIVAGDVP ESLRDKRLIA LDLGAMVAGA
260 270 280 290 300
KYRGEFEERL KAVLNEIKES NGQVITFIDE LHTVVGAGAA EGAMDAGNML
310 320 330 340 350
KPMLARGELR MIGATTLDEY RERIEKDPAL ERRFQPVYVG EPSVEDTIGI
360 370 380 390 400
LRGLKSRYEA HHKVQISDAA LVAAATLSHR FISGRFLPDK AIDLVDEAAS
410 420 430 440 450
RLRMEIDSWP VEIDELRRTV DRLRMEELAL AKEDDPASKE RLERLRRELA
460 470 480 490 500
DKQEQLNALV ARWEREKAAL NRVGELKQRL DDLRSQAERA QRDGDFETAS
510 520 530 540 550
RLMYGEIPAL ERELAAAQSS GDGHGDTMVK EEVGPDDIAE VVSSWTGIPA
560 570 580 590 600
GRLMEGEVGK LLRMEEELGR RVVGQEHAVR AVSDAVRRAR SGIADPDRPT
610 620 630 640 650
GSFLFLGPTG VGKTELAKAL ADFLFDDERA MVRIDMSEYS EKHSVARLIG
660 670 680 690 700
APPGYVGYEE GGQLTEAVRR RPYCVILLDE IEKAHVEVFD ILLQVLDDGR
710 720 730 740 750
LTDGQGRTVD FRNTILILTS NLGSNYLIDP TLDDEAKRES VMAVVRATFK
760 770 780 790 800
PEFLNRLDEI IIFNALGTAE LAKIVDLQIE RFQRRLTDRR ITLEVTPAAR
810 820 830 840 850
EWLALNGYDA VYGARPLRRL IQTAIGDRLA KALLAGDVRD GDTVLVDLTA
860
DKTGLDLRVA VPSA
Length:864
Mass (Da):95,000
Last modified:December 12, 2006 - v1
Checksum:iA22A218A78DA6ECE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000481 Genomic DNA. Translation: ABK53891.1.
RefSeqiWP_011720954.1. NC_008578.1.

Genome annotation databases

EnsemblBacteriaiABK53891; ABK53891; Acel_2119.
KEGGiace:Acel_2119.

Similar proteinsi

Entry informationi

Entry nameiA0LWT1_ACIC1
AccessioniPrimary (citable) accession number: A0LWT1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: October 25, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported