Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Ordered Locus Names:Acel_2115
OrganismiAcidothermus cellulolyticus (strain ATCC 43068 / 11B)
Taxonomic identifieri351607 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidothermalesAcidothermaceaeAcidothermus
Proteomesi
  • UP000008221 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000594971 – 618Chaperone protein DnaKAdd BLAST618

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei175Phosphothreonine; by autocatalysis1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiA0LWS7.

Expressioni

Inductioni

By stress conditions e.g. heat shock.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi351607.Acel_2115.

Structurei

3D structure databases

ProteinModelPortaliA0LWS7.
SMRiA0LWS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiISIKRHM.
OrthoDBiPOG091H01UE.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiView protein in InterPro
IPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C_sf.
IPR029047. HSP70_peptide-bd_sf.
IPR013126. Hsp_70_fam.
PfamiView protein in Pfam
PF00012. HSP70. 2 hits.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiView protein in PROSITE
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0LWS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARAVGIDLG TTNSVIAVLE GGEPTVIPNA EGSRTTPSVV AFAKNGEVLV
60 70 80 90 100
GEVAKRQAVT NAERTIRSVK RHMGTNWTID IDGKKYTPQE ISARILMKLK
110 120 130 140 150
RDAEAYLGEQ ISDAVITVPA YFNDAQRQAT KEAGQIAGLN VLRIINEPTA
160 170 180 190 200
AALAYGLDKG EKEQTILVFD LGGGTFDVSL LEIGEGIVEV KATSGDTHLG
210 220 230 240 250
GDDWDQRIVD HLVTTFKNQH GIDLSKDKMA MQRLKEAAER AKIELSSAME
260 270 280 290 300
TTINLPYITA SSEGPLHLEV KLTRSEFQRM TADLLERCKG PFNQAIKDAG
310 320 330 340 350
ITVNQIDHVI LVGGSTRMPA VVDLVRELTG GKEPNKGVNP DEVVAVGACL
360 370 380 390 400
QAGVLKGEVK DVLLLDVTPL SLGIETKGGV FTKLIERNTT IPTRRSEIFT
410 420 430 440 450
TAEDNQPSVQ IQVYQGEREI AAYNKKLGMF ELTGLPPAPR GVPQIEVTFD
460 470 480 490 500
IDANGIVHVS AKDLATGKEQ SMTITGGSAL PKEEIERMMR DAEAHAEEDR
510 520 530 540 550
RRREEAEARN QADTLIYQTE KFLRENADKV PAAEKANVET AIANLKKAME
560 570 580 590 600
GSDVTAIRSA TEQLATESQK LGAAMYAATQ AAAGGSSGSA TGATGSASGS
610
AGKDDEVVDA EIVDEGEK
Length:618
Mass (Da):66,202
Last modified:December 12, 2006 - v1
Checksum:iDA393CB351B8A067
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000481 Genomic DNA. Translation: ABK53887.1.
RefSeqiWP_011720950.1. NC_008578.1.

Genome annotation databases

EnsemblBacteriaiABK53887; ABK53887; Acel_2115.
KEGGiace:Acel_2115.

Similar proteinsi

Entry informationi

Entry nameiDNAK_ACIC1
AccessioniPrimary (citable) accession number: A0LWS7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 12, 2006
Last modified: November 22, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families