A0LWS4 (DCD_ACIC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Acel_2112

Organism

Acidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]

Taxonomic identifier

351607 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 191	191	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009669

Sequences

	Sequence		Length	Mass (Da)
	A0LWS4 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 51AEC2DEFE4B79B4	FASTA	191	21,336
	10 20 30 40 50 60 MLLSDRDIRA ELASGRVTID PFDPAMIQPS SIDVRLDKYF RVFENHRYPH IDPAVEQPDL 70 80 90 100 110 120 TRLVETEGDE PFILHPGEFV LASTYEVIAL PDDLAGRLEG KSSLGRLGLL THSTAGWIDP 130 140 150 160 170 180 GFTGHVTLEL SNVATLPIKL WPGMKIGQLC LFRTSSPAEH PYGSPVYGSR YQGQRGPTPS 190 RSWQNFHRTK I

References

[1]

"Complete sequence of Acidothermus cellulolyticus 11B." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000481 Genomic DNA. Translation: ABK53884.1.
RefSeq	YP_873870.1. NC_008578.1.
3D structure databases
ProteinModelPortal	A0LWS4.
SMR	A0LWS4. Positions 1-189.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LWS4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4484966.
GenomeReviews	Gene locus Acel_2112 in contig CP000481_GR.
KEGG	ace:Acel_2112.
PATRIC	20674882. VBIAciCel132453_2251.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	MEYFRIP.
PhylomeDB	A0LWS4.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	ACEL351607:ACEL_2112-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_ACIC1

Accession

Primary (citable) accession number: A0LWS4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program