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Reviewed, UniProtKB/Swiss-Prot A0LVX1 (IOLG_ACIC1)

Last modified November 3, 2009. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Inositol 2-dehydrogenase
    EC=1.1.1.18
Alternative name(s):
    Myo-inositol 2-dehydrogenase
      Short name=MI 2-dehydrogenase
Gene names
Name: iolG
Ordered Locus Names: Acel_1809
OrganismAcidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]
Taxonomic identifier351607 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeAcidothermaceaeAcidothermus

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity.

Catalytic activity

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP MF_01671

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the gfo/idh/mocA family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 341341Inositol 2-dehydrogenase HAMAP MF_01671
PRO_0000352549

Sequences

Sequence LengthMass (Da)Tools
A0LVX1-1 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 9B5142D9C73CA3E1

FASTA34136,761
        10         20         30         40         50         60 
MATDRSVRIG LIGAGAIGED HARRLSTVIR GADVVAVHDV DPSRAKTVAT RFRDARVIPD 

        70         80         90        100        110        120 
GNSLIGDPDV DAVVVASAAP THEAYVLAAI AARKPVFCEK PLATTAAGCL RIVEAEKAHG 

       130        140        150        160        170        180 
RRFVRVGFMR RFDPAYLGLK AELRSGAIGH PLLAHLAHRN PAVPSTLRTT DAIADSLVHE 

       190        200        210        220        230        240 
MDLVRWLFDT EIREVRAVAG RRNAKAGPDL HDPLLVLVRM ATDVVVDVEL SLNIGYGYHI 

       250        260        270        280        290        300 
RAEIVGENGT VALASEQPIV RRISGEERRP VAQHWKTRFA AAYDAELSEW VRDVSQGRVS 

       310        320        330        340 
GPSAWDGYAA TLATDAAAES LRSDTAVAAF PGDVPTLYRE P 

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References

[1]"Complete sequence of Acidothermus cellulolyticus 11B."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000481 Genomic DNA. Translation: ABK53581.1.
RefSeqYP_873567.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA0LVX1.

Genome annotation databases

GeneID4485708.
GenomeReviewsGene locus Acel_1809 in contig CP000481_GR.
KEGGace:Acel_1809.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMADWKDRFI.

Family and domain databases

HAMAPMF_01671.
[Tree]
InterProIPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIOLG_ACIC1
AccessionPrimary (citable) accession number: A0LVX1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: December 12, 2006
Last modified: November 3, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents