A0LVJ8 (MURI_ACIC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	Acel_1686

Organism

Acidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]

Taxonomic identifier

351607 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 263	263	Glutamate racemase HAMAP MF_00258		PRO_1000047539

Sequences

	Sequence		Length	Mass (Da)
	A0LVJ8 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 5CE57221ED349529	FASTA	263	28,062
	10 20 30 40 50 60 MRNLPIGVFD SGVGGLTVAR AILDLLPHEP LYYVADTAHF PYGTKSIAEV RQYGLAVLDR 70 80 90 100 110 120 MVADGVKLLV IACNSASSAL LRDARERYDV PVVEVIQPAV RKAVSATRNG KVGVIGTPAT 130 140 150 160 170 180 IASMAYDDAF AAAPHVDLTT AACPRFVEFV EAGITMSDEL LECAKEYLAP IVERGCDTLI 190 200 210 220 230 240 LGCTHYPFLA GAIALVVGDE VMLVSSADET ARDVYRVLVS RGLTRPASAP PPVHRFAATG 250 260 DPEPFSRLGR RFLGPEIGHV TTL

References

[1]

"Complete sequence of Acidothermus cellulolyticus 11B." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000481 Genomic DNA. Translation: ABK53458.1.
RefSeq	YP_873444.1. NC_008578.1.
3D structure databases
ProteinModelPortal	A0LVJ8.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LVJ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4486044.
GenomeReviews	Gene locus Acel_1686 in contig CP000481_GR.
KEGG	ace:Acel_1686.
PATRIC	20673948. VBIAciCel132453_1796.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0796.
HOGENOM	HBG645102.
OMA	PQEDTIY.
PhylomeDB	A0LVJ8.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	ACEL351607:ACEL_1686-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_ACIC1

Accession

Primary (citable) accession number: A0LVJ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program