ID   A0LVI2_ACIC1            Unreviewed;       527 AA.
AC   A0LVI2;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=DNA primase-like protein {ECO:0000313|EMBL:ABK53442.1};
GN   OrderedLocusNames=Acel_1670 {ECO:0000313|EMBL:ABK53442.1};
OS   Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B).
OC   Bacteria; Actinomycetota; Actinomycetes; Acidothermales; Acidothermaceae;
OC   Acidothermus.
OX   NCBI_TaxID=351607 {ECO:0000313|EMBL:ABK53442.1, ECO:0000313|Proteomes:UP000008221};
RN   [1] {ECO:0000313|EMBL:ABK53442.1, ECO:0000313|Proteomes:UP000008221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43068 / DSM 8971 / 11B
RC   {ECO:0000313|Proteomes:UP000008221};
RX   PubMed=19270083; DOI=10.1101/gr.084848.108;
RA   Barabote R.D., Xie G., Leu D.H., Normand P., Necsulea A., Daubin V.,
RA   Medigue C., Adney W.S., Xu X.C., Lapidus A., Parales R.E., Detter C.,
RA   Pujic P., Bruce D., Lavire C., Challacombe J.F., Brettin T.S., Berry A.M.;
RT   "Complete genome of the cellulolytic thermophile Acidothermus
RT   cellulolyticus 11B provides insights into its ecophysiological and
RT   evolutionary adaptations.";
RL   Genome Res. 19:1033-1043(2009).
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DR   EMBL; CP000481; ABK53442.1; -; Genomic_DNA.
DR   RefSeq; WP_011720505.1; NC_008578.1.
DR   AlphaFoldDB; A0LVI2; -.
DR   STRING; 351607.Acel_1670; -.
DR   KEGG; ace:Acel_1670; -.
DR   eggNOG; COG1793; Bacteria.
DR   eggNOG; COG3285; Bacteria.
DR   HOGENOM; CLU_008325_6_1_11; -.
DR   InParanoid; A0LVI2; -.
DR   OrthoDB; 9802472at2; -.
DR   Proteomes; UP000008221; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd04865; LigD_Pol_like_2; 1.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014144; LigD_PE_domain.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02777; LigD_PE_dom; 1.
DR   NCBIfam; TIGR02778; ligD_pol; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF13298; LigD_N; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008221}.
FT   DOMAIN          45..152
FT                   /note="DNA ligase D 3'-phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF13298"
FT   DOMAIN          260..513
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
FT   REGION          12..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   527 AA;  60093 MW;  0928BA0BA5CD73C3 CRC64;
     MADRRPGDLR EYRRRRNFCR TPEPAGRADP RHITRNSAEP RFVVQRHRAT RLHYDLRLEI
     NGVLVSWAVP KGPTLDPTVR RAAIHVEDHP LEYLDFEGAI PHGEYGGGDV IVWDTGTWRP
     HGTDDPAQAV VDGELHADFF GRKLRGRFVF VRRGTDEKSW LVLHKDDEHA VRGWNPEDYP
     RSVLSGATND DVARHPRRLW RGGRAHPVAQ HNDTEASADE IAALDALDDE GTWEVFGRRL
     KVTHLNKVIY PGRGRTHALT KRDLLRYAAR IAPVVMPYLA GRPFTMHRFP DGIDAPGFWH
     KQLPSHAPDW LPRWQNPSAK RGEAATYLVV DEPAALIWAV NFGAIEWHAW TSRTDRPDLP
     TWALVDIDPG SRTTWRELVE LALLHRDALD HLGVQGKPKL TGQRGIQIWI PIRRGPTFDD
     TRAWVEHLSK VVGSLMPDAV SWEWEKKRRA GRARLDFTQN AANKTLVAPY SPRPLPRAPV
     SAPVEWDELP HLRPDRFTVR TILDRLAERG DPFHALLTVN QQLPPLG
//