A0LUW0 (A0LUW0_ACIC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Periplasmic sensor signal transduction histidine kinase EMBL ABK53220.1

Gene names

Ordered Locus Names:

Acel_1448

Organism

Acidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]

Taxonomic identifier

351607 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length	524 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. SAAS SAAS003660
Subcellular location	Membrane; Multi-pass membrane protein By similarity RuleBase RU003568.
Sequence similarities	Contains 1 histidine kinase domain. SAAS SAAS009082

Ontologies

Keywords
Biological process	Two-component regulatory system SAAS SAAS005467
Cellular component	Membrane
Domain	Signal EMBL ABK53220.1 Transmembrane SAAS SAAS005467 RuleBase RU003568
Ligand	ATP-binding SAAS SAAS005467 Nucleotide-binding
Molecular function	Kinase SAAS SAAS004358 RuleBase RU003568 EMBL ABK53220.1 Transferase
PTM	Phosphoprotein SAAS SAAS005467 RuleBase RU003568
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	peptidyl-histidine phosphorylation Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW two-component sensor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 36	36	Potential EMBL ABK53220.1
	Chain	37 – 524	488	Potential EMBL ABK53220.1		PRO_5000166657

Sequences

	Sequence		Length	Mass (Da)
	A0LUW0 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 367DF68820CC6D72	FASTA	524	56,580
	10 20 30 40 50 60 MKSPLSPPRF WHSLSLRGRL LIGVLGLVAL GLAVAALATR ALLASFLLNR FDNDQQAATR 70 80 90 100 110 120 LVAQMVFADG GPGRALFGAP GRRGAVTRLL PVGSYAAAVT AGGRVVEQFG YDATDAWVPV 130 140 150 160 170 180 SAAEAPRLPS DVASRTAPFT AYTPSGAAYR MVVVPQLLVN PTTGVRYTFV WGMPLREVDA 190 200 210 220 230 240 TLRRLTIVEI AVAVGVLVGV GYLAWFVLGL GLRPLRAIER AADDIAAGQL SRRVAYADTR 250 260 270 280 290 300 NEVGRLGAAF NTMVSRIEEA FAVRAASEER LRRFLADASH ELRTPLTSIR GYAELFRRGA 310 320 330 340 350 360 ARRPDDLEKA MRRIEEEATR MGVLVDELLL LARLDQGRQP VREPVLLAEL VADACEDFRA 370 380 390 400 410 420 AAPDRQVRVD ADPDVVVSGD ELQLRQVVTN LLTNVRVHTP PGTPVDIRLA AENGWAVLEV 430 440 450 460 470 480 TDYGLGLPAA DLPRVFDRFY RADPSRTRDH GGAGLGLAIV ASVVQAHGGR VGVRNVPGAG 490 500 510 520 ACFRVELPLL AEFPSNSQLT PNLQGQVNQM MEPDLKEAMN DRNT

References

[1]

"Complete sequence of Acidothermus cellulolyticus 11B." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000481 Genomic DNA. Translation: ABK53220.1.
RefSeq	YP_873206.1. NC_008578.1.
3D structure databases
ProteinModelPortal	A0LUW0.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LUW0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4485085.
GenomeReviews	Gene locus Acel_1448 in contig CP000481_GR.
KEGG	ace:Acel_1448.
PATRIC	20673418. VBIAciCel132453_1537.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0642.
HOGENOM	HBG334875.
OMA	LANVRTH.
PhylomeDB	A0LUW0.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR003660. HAMP_linker_domain. IPR004358. Sig_transdc_His_kin-like_C. IPR003661. Sig_transdc_His_kin_sub1_dim/P. IPR005467. Sig_transdc_His_kinase_core. IPR009082. Sig_transdc_His_kinase_dimeric. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
KO	K02484.
Pfam	PF00672. HAMP. 1 hit. PF02518. HATPase_c. 1 hit. PF00512. HisKA. 1 hit. [Graphical view]
PRINTS	PR00344. BCTRLSENSOR.
SMART	SM00304. HAMP. 1 hit. SM00387. HATPase_c. 1 hit. SM00388. HisKA. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF47384. His_kin_homodim. 1 hit.
PROSITE	PS50885. HAMP. 1 hit. PS50109. HIS_KIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0LUW0_ACIC1

Accession

Primary (citable) accession number: A0LUW0

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)