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A0LUR9 (A0LUR9_ACIC1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Acel_1407
OrganismAcidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]
Taxonomic identifier351607 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length350 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1891Iron By similarity HAMAP MF_00323
Metal binding2751Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A0LUR9 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 7E5C5CF33BF54C53

FASTA35037,873
        10         20         30         40         50         60 
MTTSQTEPPT YDALLIVSFG GPEGPDDVMP FLRDVTAGRG VPEERLAEVA QHYYHFGGIS 

        70         80         90        100        110        120 
PINAQNRALL AAVRADFAAT GVNLAVYWAN RHWQPWLADV VAQMRDDGIE RALAFLTSAY 

       130        140        150        160        170        180 
AGFSSCRQYL DAIEAARRRV GPRAPRIDRL RQYFNHPGFI EPFRDATQSA LATLPPEVRA 

       190        200        210        220        230        240 
GAPIVYVAHS IPEAMNAASG PAGGMYARQV AEAARLVHEA LDGSHPSRLA YCSRSGSPSV 

       250        260        270        280        290        300 
PWLEPEIGQV LTELAEDGAP AVVVVPIGFV SDHMEVRYDL DTEAAELAAR LGVRFARAAT 

       310        320        330        340        350 
PGTDPRFVAM IRELALERLG RAAPRALGPT SPAHDVCPDN CCRFARSHPA

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References

[1]"Complete sequence of Acidothermus cellulolyticus 11B."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000481 Genomic DNA. Translation: ABK53179.1.
RefSeqYP_873165.1. NC_008578.1.

3D structure databases

ProteinModelPortalA0LUR9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0LUR9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4486631.
GenomeReviewsGene locus Acel_1407 in contig CP000481_GR.
KEGGace:Acel_1407.
PATRIC20673330. VBIAciCel132453_1493.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAPAVVMAP.
PhylomeDBA0LUR9.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0LUR9_ACIC1
AccessionPrimary (citable) accession number: A0LUR9
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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