A0LSP3 (A0LSP3_ACIC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphorylase RuleBase RU000587
EC=2.4.1.1 RuleBase RU000587

Gene names

Ordered Locus Names:

Acel_0680

Organism

Acidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]

Taxonomic identifier

351607 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length	875 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587
Molecular function	Glycosyltransferase RuleBase RU000587 EMBL ABK52453.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0LSP3 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 90C643323FE05B02	FASTA	875	96,377
	10 20 30 40 50 60 MRAIRRFTVR TVLPPRLAGL AELVMNLRWS WHPPTLELFA AIDPLVWRAV RGDPVRLLGE 70 80 90 100 110 120 VPPSRLAELA ADEGFLRRLD HALEDLHAYL TGDRWYQTTA VDGPRAVAYF SPEYGITSVL 130 140 150 160 170 180 PQYSGGLGIL AGDHLKTASD LGIPLIGVGL LYRRGYFNQS LSRDGWQQER YPPIDPYGLP 190 200 210 220 230 240 LELLTEADGS PVSIAIQLPE QRTLQARVWQ ARVGRVPLLL LDSDVEGNAP AERDVTDRLY 250 260 270 280 290 300 GGGTDHRFRQ ELLLGVGGVR AVRAFCRITG HPEPEVYHMN EGHAGFLALE RISELMQDAG 310 320 330 340 350 360 LSFDEALEVV RASTVFTTHT PVPAGIDRFP RDLIERHLVA ETDGPARDGL HILPADRVLA 370 380 390 400 410 420 LGAEAYPGGD PGVFNMAVLG LRVASRANGV STLHGAVSRH MFAGLWPNFD PDDVPITSVT 430 440 450 460 470 480 NGVHVPTWLA GEMRTLLETE LAGPAGVDGA GEGIRWADAE RLDDVRLWQV RNALRARLVV 490 500 510 520 530 540 EARARLRESW RTRGATDSEM QWIDDALDPQ VLTIGFARRV PSYKRLTLML RNPERLRALL 550 560 570 580 590 600 LHPRHPVQIV IAGKAHPADD AGKRLIQEVV KFADDPEVRH RIVFLPDYDM ALAQLLIAGA 610 620 630 640 650 660 DVWLNNPLRP LEACGTSGMK AALNGVLNLS IRDGWWDEWF DGNNGWAIPS ADGLPDDRRD 670 680 690 700 710 720 DLEAHALYDI IESQVAPRFY DRGSDGLPTR WLEMIRHAIA SLGPKVAATR MLREYLDRLY 730 740 750 760 770 780 TPAACAHRAV TADDFAGARH LAAWKARILQ AWPGVRVEHV AASGLADALE YGTRVPVRAV 790 800 810 820 830 840 VALGGLDPSD VDVQVVYGRV DENDELVTPR SASLRPTDAR DGLFGYEGEI VLDRTGPFGY 850 860 870 SVRVLPRDTL LGVSAELGLV ALPPPRESIT SGDLR

References

[1]

"Complete sequence of Acidothermus cellulolyticus 11B." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000481 Genomic DNA. Translation: ABK52453.1.
RefSeq	YP_872439.1. NC_008578.1.
3D structure databases
ProteinModelPortal	A0LSP3.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LSP3.
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4486236.
GenomeReviews	Gene locus Acel_0680 in contig CP000481_GR.
KEGG	ace:Acel_0680.
PATRIC	20671754. VBIAciCel132453_0722.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0058.
HOGENOM	HBG302557.
OMA	LRWSWHP.
PhylomeDB	A0LSP3.
Family and domain databases
InterPro	IPR011834. Agluc_phsphrylas. IPR000811. Glyco_trans_35. IPR024517. Glycogen_phosphorylase_DUF3417. [Graphical view]
KO	K00688.
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF11897. DUF3417. 1 hit. PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02094. More_P_ylases. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0LSP3_ACIC1

Accession

Primary (citable) accession number: A0LSP3

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)