A0LSJ1 (A0LSJ1_ACIC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP MF_00123
EC=6.1.1.19 HAMAP MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP MF_00123

Gene names

Name:	argS HAMAP MF_00123
Ordered Locus Names:	Acel_0628

Organism

Acidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]

Taxonomic identifier

351607 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length	562 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm By similarity HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00123 RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00123 RuleBase RU003489
Cellular component	Cytoplasm HAMAP MF_00123
Ligand	ATP-binding HAMAP MF_00123 RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP MF_00123 RuleBase RU003489 EMBL ABK52401.1 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Motif	141 – 151	11	"HIGH" region By similarity HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	A0LSJ1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 0799437D8971A3AD	FASTA	562	61,839
	10 20 30 40 50 60 MPARRRCGSL APVTPADLAD AIRRAIRAAV DADQLRVDVP AEVLVERPKR KEFGDYATNV 70 80 90 100 110 120 ALQLAKSAGR PPRDVAAILA EQLAAQPGIA AVDVAGPGFL NIRLAAGAQG DIARQIVEAG 130 140 150 160 170 180 PRYGTSTTLR GQRINVEFVS ANPTGPLHLG HTRWAAVGDA LARVLQAAGA EVTREFYIND 190 200 210 220 230 240 RGAQMEKFGA SLAAAAVGEP IPDDGYHGRY IHDLAKEIAG EHPEFLDLPP DERAAAFRDE 250 260 270 280 290 300 GYRRQLERQR RALEHFRVHF DVWFSERVLH ESGAVEAALD ELRRQGHVYE ADGAVWLRTT 310 320 330 340 350 360 DFGDDRDRVL VRSNGEKTYF AADAAYYLDK RRRGFDTCLY LLGADHHGYV ARLKAIAACA 370 380 390 400 410 420 GDDPERTLEV LIGQLVKILK GGEEVRLSKR AGEIVTLEDV VDLAGVDAVR YSLARYPADS 430 440 450 460 470 480 PLTLDVDLIT RQTNDNPVFY VQYVAARTAS VSRHARDLGI DRGAFDPTLL GHDREIDLLG 490 500 510 520 530 540 ALAEFPRIVA SAAELREPHR IARYLEELAG TYHRFYDACR ILPVGDEQPT PLTHARLWLN 550 560 DATRIVIANG LELLGVEAPE RM

References

[1]

"Complete sequence of Acidothermus cellulolyticus 11B." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000481 Genomic DNA. Translation: ABK52401.1.
RefSeq	YP_872387.1. NC_008578.1.
3D structure databases
ProteinModelPortal	A0LSJ1.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LSJ1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4485534.
GenomeReviews	Gene locus Acel_0628 in contig CP000481_GR.
KEGG	ace:Acel_0628.
PATRIC	20671652. VBIAciCel132453_0671.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HBG695395.
OMA	RMKAAMK.
ProtClustDB	PRK01611.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K01887.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. ArgS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0LSJ1_ACIC1

Accession

Primary (citable) accession number: A0LSJ1

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)