A0LSE9 (A0LSE9_ACIC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase E1 component EMBL ABK52359.1
EC=1.2.4.2 EMBL ABK52359.1

Gene names

Ordered Locus Names:

Acel_0586

Organism

Acidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]

Taxonomic identifier

351607 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length	1233 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Molecular function	Oxidoreductase EMBL ABK52359.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0LSE9 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: F388882FB8E3EEDD	FASTA	1,233	135,019
	10 20 30 40 50 60 MAQTATSASH SFAEFGANEW LVDEMYQRYL HDPNSVDPAW WDFFADYVPR DRPAPAATAT 70 80 90 100 110 120 ASAAGAPART TIGDAATRAA GAGGGTAVME AATAGGAAAT RVIETPAPEA EPIPSRGDGL 130 140 150 160 170 180 AAQAVPLKGS AARTASNMTA SLTIPTATSV REIPAKLLID NRLVMNNHLR RGRGGKISFT 190 200 210 220 230 240 HIIGYAVVKA ALAHPEMNVA YTEVNGRPGV IQYPDVNLGL AIDVTRDDGT RQLLVPCIKA 250 260 270 280 290 300 AQRMDFAQFW VAYEDLVRRA RSGKLTPDDF TGTTLTLTNP GTIGTVHSVP RLMPGQGCII 310 320 330 340 350 360 GVGAMEYPAQ FQGAAEETLA NLAVSKVLTL TSTYDHRVIQ GAQSGEFLRH IHRLLLGEEG 370 380 390 400 410 420 FYDELFRALR IPYEPVRWVK DIVASHADEV GKQARVVELI HAYRVRGHLM ADTNPLEFEM 430 440 450 460 470 480 RRHPDLDIVN HGLTLWDLDR KFATGGFAGE PVMRLRDILG VLRDSYCRTV GVEYMHIQDP 490 500 510 520 530 540 EQRRWIQQRV EQPQQRLDRD EQLYILKRLN VAEAFETFLQ TKYVGQRRFS LEGAETLIPL 550 560 570 580 590 600 LDTIIDAAAH QGLDEVVIGM AHRGRLNVLA NIVGKSYAQI FREFEGYLDP ASTHGSGDVK 610 620 630 640 650 660 YHLGAEGRYT TRDGTKDIKV SLVSNPSHLE AVDPVLEGIV RAKQDLLNKG AEYPVLPLAI 670 680 690 700 710 720 HGDAAFAGQG VVAETLNLSQ LRGYRTGGTI HVVVNNQVGF TTAPSAARSS VYATDVARMI 730 740 750 760 770 780 QAPIFHVNGD DPEAAVRVAR IALDFRQAFK KDVVIDLVCY RRRGHNEADD PSMTQPLMYD 790 800 810 820 830 840 LIDAKRSVRK LYTEALIGRG DIGIDEAEAA LRDYRARLEE AFAETKDSAP PRPSSPPQRA 850 860 870 880 890 900 TPPAPAAVDT SISVATLKRI AESQVNLPPG FTPHPRLVPL LQRRAAMVDS DAIDWPMAEL 910 920 930 940 950 960 IAFGSLMLEG HPVRLAGQDS RRGTFVQRHA VLVDRKTGAE YTPLAHLDPN QAPFYIYDSL 970 980 990 1000 1010 1020 LSEFAALGFE YGYSVVRSDA LVAWEAQFGD FANGAQTIID EFISSGEQKW GQRSGLVLLL 1030 1040 1050 1060 1070 1080 PHGYEGQGPD HSSGRIERFL QLCAQENMTV AVPSCAASYF HLLRWHVLSQ VRRPLVVFTP 1090 1100 1110 1120 1130 1140 KSMLRAKSAA SPASAFTAGR WSPVLGDPDP RDPAEVRRVL LCSGKIAWEL VERRAAQQRT 1150 1160 1170 1180 1190 1200 DTAILRVEQL YPLPGEEIQA ALAAFPRLDE VVWVQEEPVN MGAWPFIALH LAPTLGSGMR 1210 1220 1230 CIARPESSAP ATGSHVRSEE EQRELLAAAL PES

References

[1]

"Complete sequence of Acidothermus cellulolyticus 11B." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000481 Genomic DNA. Translation: ABK52359.1.
RefSeq	YP_872345.1. NC_008578.1.
3D structure databases
ProteinModelPortal	A0LSE9.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LSE9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4484820.
GenomeReviews	Gene locus Acel_0586 in contig CP000481_GR.
KEGG	ace:Acel_0586.
PATRIC	20671558. VBIAciCel132453_0625.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0567.
HOGENOM	HBG289950.
OMA	EGDEPAF.
PhylomeDB	A0LSE9.
ProtClustDB	PRK12270.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K00164.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0LSE9_ACIC1

Accession

Primary (citable) accession number: A0LSE9

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)