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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:Acel_0363
OrganismiAcidothermus cellulolyticus (strain ATCC 43068 / 11B)
Taxonomic identifieri351607 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidothermalesAcidothermaceaeAcidothermus
Proteomesi
  • UP000008221 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003319621 – 54160 kDa chaperonin 2Add BLAST541

Proteomic databases

PRIDEiA0LRS7.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi351607.Acel_0363.

Structurei

3D structure databases

ProteinModelPortaliA0LRS7.
SMRiA0LRS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiCVIKVGA.
OrthoDBiPOG091H00E7.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A0LRS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKLLYYAED ARGALQRGVD HLADTVKVTL GPKGRNVVLA TSGNKVTITN
60 70 80 90 100
DGVTIAREIE LDERDENLGA QLVKEVATKT NDVAGDGTTT ATVLAQAMVR
110 120 130 140 150
EGLRNVAAGA NPLALKRGID AAVTAISDRL LAQAREVATK DEIANVATIS
160 170 180 190 200
AQDPAVGAVI ADAFDKVGKD GVITVEESNT MGLELEFVEG LQFDKGYISP
210 220 230 240 250
YFITDPERME AVLDNPYILL HEGKISNAMD FVPLLEKVVQ AGRPLLVIAE
260 270 280 290 300
DVEGDALATL VVNKIRGTFS SVAVKAPGFG DRRKAMLGDM AVLTGAQVVS
310 320 330 340 350
PEVGLKLDEV GLEVLGTARR VRVTRDDTTI VEGGGSAEAI QDRIRQIRAQ
360 370 380 390 400
IDQTDSDWDR EKLQERLAKL AGGVAVIRVG AATEVELKEK KHRLEDAVSA
410 420 430 440 450
TRAAIEEGIV AGGGSALLHA SSALDSLELT GDEAVGASIV RKAAAEPLRW
460 470 480 490 500
IAENAGFEGY VVCSRVRDLP VGHGFDAQTG EYTDLVARGI IDPVKVTRSA
510 520 530 540
LTNAASVVGL LLTTEAIVVD KPEEKPESAG HNHGHGHHHP H
Length:541
Mass (Da):57,306
Last modified:December 12, 2006 - v1
Checksum:i67729E6CD663DE7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000481 Genomic DNA. Translation: ABK52137.1.
RefSeqiWP_011719200.1. NC_008578.1.

Genome annotation databases

EnsemblBacteriaiABK52137; ABK52137; Acel_0363.
KEGGiace:Acel_0363.

Similar proteinsi

Entry informationi

Entry nameiCH602_ACIC1
AccessioniPrimary (citable) accession number: A0LRS7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 12, 2006
Last modified: June 7, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families