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A0LRR9

- A0LRR9_ACIC1

UniProt

A0LRR9 - A0LRR9_ACIC1

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Protein

Alanine racemase

Gene

Acel_0355

Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei59 – 591Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei157 – 1571SubstrateUniRule annotation
Active sitei291 – 2911Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei340 – 3401Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciACEL351607:GIXW-367-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Acel_0355Imported
OrganismiAcidothermus cellulolyticus (strain ATCC 43068 / 11B)Imported
Taxonomic identifieri351607 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeAcidothermaceaeAcidothermus
ProteomesiUP000008221: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei59 – 591N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi351607.Acel_0355.

Structurei

3D structure databases

ProteinModelPortaliA0LRR9.
SMRiA0LRR9. Positions 27-403.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiGHTWTAQ.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0LRR9 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVSGARGSP AWAAEELAGP ELGVARASRA QAVVDLGAIR ENVRRLRAVT
60 70 80 90 100
GVDVMAVVKA DGYGHGLLPA ARAAVRGGAS WLGVAFVEEA LALRMAGIDV
110 120 130 140 150
PILCLLAAPG ERFAEAIAAD VDLAVSAEWA LSEVCRAATT AGRTARIHLE
160 170 180 190 200
VDTGLSRGGA TPAEWPDLLA ATAQARAAGL VEVVGIWSHL VHGDNPEHAD
210 220 230 240 250
TTVQVERFDE ALAVAERFGI RPAVRHLANS GGALLAPRTR YDLVRPGIAV
260 270 280 290 300
YGLSPAPALV SAGELGLRPA MHLRAQVALV KELPAGEGIS YGHRYRTLRP
310 320 330 340 350
TRVALIPLGY ADGIPRQATN VAPVWFPAVG RRTISGTVCM DQFVVDVGPD
360 370 380 390 400
APVAAGDDVV IFGPGDDGEP TADEWASAVG TISYEIVSRI GARVPRVYRD

DDTAG
Length:405
Mass (Da):42,200
Last modified:December 12, 2006 - v1
Checksum:i22D95F5798F14ECE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000481 Genomic DNA. Translation: ABK52129.1.
RefSeqiWP_011719192.1. NC_008578.1.
YP_872115.1. NC_008578.1.

Genome annotation databases

EnsemblBacteriaiABK52129; ABK52129; Acel_0355.
GeneIDi4485894.
KEGGiace:Acel_0355.
PATRICi20671076. VBIAciCel132453_0385.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000481 Genomic DNA. Translation: ABK52129.1 .
RefSeqi WP_011719192.1. NC_008578.1.
YP_872115.1. NC_008578.1.

3D structure databases

ProteinModelPortali A0LRR9.
SMRi A0LRR9. Positions 27-403.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351607.Acel_0355.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK52129 ; ABK52129 ; Acel_0355 .
GeneIDi 4485894.
KEGGi ace:Acel_0355.
PATRICi 20671076. VBIAciCel132453_0385.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi GHTWTAQ.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci ACEL351607:GIXW-367-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43068 / 11BImported.

Entry informationi

Entry nameiA0LRR9_ACIC1
AccessioniPrimary (citable) accession number: A0LRR9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3