A0LRQ7 (GLMM_ACIC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Acel_0343

Organism

Acidothermus cellulolyticus (strain ATCC 43068 / 11B) [Complete proteome] [HAMAP]

Taxonomic identifier

351607 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Acidothermaceae › Acidothermus

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 461	461	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000305630
Sites
	Active site	118	1	Phosphoserine intermediate By similarity
	Metal binding	118	1	Magnesium; via phosphate group By similarity
	Metal binding	255	1	Magnesium By similarity
	Metal binding	257	1	Magnesium By similarity
	Metal binding	259	1	Magnesium By similarity
Amino acid modifications
	Modified residue	118	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0LRQ7 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 8F5F0889D96BB30B	FASTA	461	47,715
	10 20 30 40 50 60 MAVSGTAAGT GLASTPRLFG TDGVRGIANR DLTAELALDL AVAAAHVLAQ AGAFEGHRPL 70 80 90 100 110 120 AVVGRDPRAS GEFLEAAVVA GLASAGVDVL RLGVLPTPAV AYLTAALDAD LGVVLSASHN 130 140 150 160 170 180 PMPDNGIKFL ARGGHKLPDD IEDAVAARLG EPWTRPVGRF VGRVRDYPEG LDQYVEHVLA 190 200 210 220 230 240 TSDQRLDGLR VVVDCAHGAA SVVSPAVLRR AGATVVPIGC EPDGYNINDG HGSTNIETLQ 250 260 270 280 290 300 AAVRREGADA GIAHDGDADR CLAVDAAGDV VDGDQILAIL ALAWQEAGRL AHDTVVATVM 310 320 330 340 350 360 SNLGLKLGLA AHGISVVETA VGDRYVLEAM RAGGYVLGGE QSGHIIMLDY ATTGDGVLTG 370 380 390 400 410 420 LQLLGRMAAT GRPLADLARV VRRLPQVLRN VTGVDKTRVD TDPVINKELA AARGELGDGG 430 440 450 460 RVLLRASGTE PVVRVMVEAE TEADAERVAE RLARVVRERL G

References

[1]

"Complete sequence of Acidothermus cellulolyticus 11B." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Berry A.M., Adney W.S., Normand P., Leu D., Pujic P., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43068 / 11B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000481 Genomic DNA. Translation: ABK52117.1.
RefSeq	YP_872103.1. NC_008578.1.
3D structure databases
ProteinModelPortal	A0LRQ7.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LRQ7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4486411.
GenomeReviews	Gene locus Acel_0343 in contig CP000481_GR.
KEGG	ace:Acel_0343.
PATRIC	20671048. VBIAciCel132453_0371.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Enzyme and pathway databases
BioCyc	ACEL351607:ACEL_0343-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ACIC1

Accession

Primary (citable) accession number: A0LRQ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program