A0LRJ4NUON_ACIC1NADH-quinone oxidoreductase subunit N7.1.1.-NADH dehydrogenase I subunit NNDH-1 subunit NnuoNAcel_0280Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B)BacteriaActinomycetotaActinomycetesAcidothermalesAcidothermaceaeAcidothermusComplete genome of the cellulolytic thermophile Acidothermus cellulolyticus 11B provides insights into its ecophysiological and evolutionary adaptations.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.Cell membraneMulti-pass membrane proteinBelongs to the complex I subunit 2 family.Cell membraneMembraneNADQuinoneReference proteomeTranslocaseTransmembraneTransmembrane helixTransportMSFYAAANPNAIPAPHIEYRALLPMLIVFGVACAGVLVEAFVPRAQRALTQTVLALGGLVAALIAVVSNTGLPRKLVAQSAIAADGPTLFIQGTILALSIGALLLIADRSIGADSDFVAQAADLPGSEQERASVQAGLRQTEVFPLAMFAVGGMMLFPAANDLITAFVALEVLSLPLYLLAGMARRRRLLSQEAAVKYFLLGAFSSAFFVYGLALVYGYAKSVEYGDIATALTASDRGDSLIIVGLALIGISLLFKLSGVPFHWWTPDVYQGAPTPITAFMAAGTKVAAFGALLRVFFVAFGGLAWDWRPVIWGVAIATMVVGAILGITQTDVKRLLAYSSIAHAGFVLTAFAATTRASESSVLFYLVAYGFMTIGAFAIVILVRDGDGEANHLSRWVGLGRRSPLVAGIFALFLLAMAGLPPTSGLWAKVAVFTAAYQGGAGPLVIVGVLASAVTAYYYLRIIVLMFAQEPAVEGPTVAVPGALASAAIALGVIVTVVLGIVPQPVLDLADKAVPFLR
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