SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0LRJ4

- NUON_ACIC1

UniProt

A0LRJ4 - NUON_ACIC1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

NADH-quinone oxidoreductase subunit N

Gene
nuoN, Acel_0280
Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity.UniRule annotation

Catalytic activityi

NADH + quinone = NAD+ + quinol.UniRule annotation

GO - Molecular functioni

  1. NADH dehydrogenase (ubiquinone) activity Source: InterPro
  2. quinone binding Source: UniProtKB-KW

GO - Biological processi

  1. ATP synthesis coupled electron transport Source: InterPro
  2. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Transport

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciACEL351607:GIXW-288-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit N (EC:1.6.99.5)
Alternative name(s):
NADH dehydrogenase I subunit N
NDH-1 subunit N
Gene namesi
Name:nuoN
Ordered Locus Names:Acel_0280
OrganismiAcidothermus cellulolyticus (strain ATCC 43068 / 11B)
Taxonomic identifieri351607 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeAcidothermaceaeAcidothermus
ProteomesiUP000008221: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei22 – 4221Helical; Reviewed predictionAdd
BLAST
Transmembranei53 – 7321Helical; Reviewed predictionAdd
BLAST
Transmembranei87 – 10721Helical; Reviewed predictionAdd
BLAST
Transmembranei141 – 16121Helical; Reviewed predictionAdd
BLAST
Transmembranei163 – 18321Helical; Reviewed predictionAdd
BLAST
Transmembranei198 – 21821Helical; Reviewed predictionAdd
BLAST
Transmembranei242 – 26221Helical; Reviewed predictionAdd
BLAST
Transmembranei287 – 30721Helical; Reviewed predictionAdd
BLAST
Transmembranei310 – 33021Helical; Reviewed predictionAdd
BLAST
Transmembranei336 – 35621Helical; Reviewed predictionAdd
BLAST
Transmembranei363 – 38321Helical; Reviewed predictionAdd
BLAST
Transmembranei406 – 42621Helical; Reviewed predictionAdd
BLAST
Transmembranei442 – 46120Helical; Reviewed predictionAdd
BLAST
Transmembranei483 – 50321Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 519519NADH-quinone oxidoreductase subunit NUniRule annotationPRO_0000391089Add
BLAST

Keywords - PTMi

Quinone

Interactioni

Subunit structurei

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex By similarity.

Protein-protein interaction databases

STRINGi351607.Acel_0280.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1007.
HOGENOMiHOG000100794.
KOiK00343.
OMAiSATMFYL.
OrthoDBiEOG64JFNZ.

Family and domain databases

HAMAPiMF_00445. NDH1_NuoN_1.
InterProiIPR010096. NADH-Q_OxRdtase_suN/2.
IPR001750. NADH_UbQ/plastoQ_OxRdtase.
[Graphical view]
PfamiPF00361. Oxidored_q1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01770. NDH_I_N. 1 hit.

Sequencei

Sequence statusi: Complete.

A0LRJ4-1 [UniParc]FASTAAdd to Basket

« Hide

MSFYAAANPN AIPAPHIEYR ALLPMLIVFG VACAGVLVEA FVPRAQRALT    50
QTVLALGGLV AALIAVVSNT GLPRKLVAQS AIAADGPTLF IQGTILALSI 100
GALLLIADRS IGADSDFVAQ AADLPGSEQE RASVQAGLRQ TEVFPLAMFA 150
VGGMMLFPAA NDLITAFVAL EVLSLPLYLL AGMARRRRLL SQEAAVKYFL 200
LGAFSSAFFV YGLALVYGYA KSVEYGDIAT ALTASDRGDS LIIVGLALIG 250
ISLLFKLSGV PFHWWTPDVY QGAPTPITAF MAAGTKVAAF GALLRVFFVA 300
FGGLAWDWRP VIWGVAIATM VVGAILGITQ TDVKRLLAYS SIAHAGFVLT 350
AFAATTRASE SSVLFYLVAY GFMTIGAFAI VILVRDGDGE ANHLSRWVGL 400
GRRSPLVAGI FALFLLAMAG LPPTSGLWAK VAVFTAAYQG GAGPLVIVGV 450
LASAVTAYYY LRIIVLMFAQ EPAVEGPTVA VPGALASAAI ALGVIVTVVL 500
GIVPQPVLDL ADKAVPFLR 519
Length:519
Mass (Da):54,151
Last modified:December 12, 2006 - v1
Checksum:i50D0124954A29947
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000481 Genomic DNA. Translation: ABK52054.1.
RefSeqiWP_011719117.1. NC_008578.1.
YP_872040.1. NC_008578.1.

Genome annotation databases

EnsemblBacteriaiABK52054; ABK52054; Acel_0280.
GeneIDi4486543.
KEGGiace:Acel_0280.
PATRICi20670910. VBIAciCel132453_0306.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000481 Genomic DNA. Translation: ABK52054.1 .
RefSeqi WP_011719117.1. NC_008578.1.
YP_872040.1. NC_008578.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351607.Acel_0280.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK52054 ; ABK52054 ; Acel_0280 .
GeneIDi 4486543.
KEGGi ace:Acel_0280.
PATRICi 20670910. VBIAciCel132453_0306.

Phylogenomic databases

eggNOGi COG1007.
HOGENOMi HOG000100794.
KOi K00343.
OMAi SATMFYL.
OrthoDBi EOG64JFNZ.

Enzyme and pathway databases

BioCyci ACEL351607:GIXW-288-MONOMER.

Family and domain databases

HAMAPi MF_00445. NDH1_NuoN_1.
InterProi IPR010096. NADH-Q_OxRdtase_suN/2.
IPR001750. NADH_UbQ/plastoQ_OxRdtase.
[Graphical view ]
Pfami PF00361. Oxidored_q1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01770. NDH_I_N. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43068 / 11B.

Entry informationi

Entry nameiNUON_ACIC1
AccessioniPrimary (citable) accession number: A0LRJ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: December 12, 2006
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi