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A0LPA9

- G6PI_SYNFM

UniProt

A0LPA9 - G6PI_SYNFM

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei515 – 5151UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSFUM335543:GH6P-3646-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Sfum_3591
OrganismiSyntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Taxonomic identifieri335543 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophobacteraceaeSyntrophobacter
ProteomesiUP000001784: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Glucose-6-phosphate isomerasePRO_1000014029Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi335543.Sfum_3591.

Structurei

3D structure databases

ProteinModelPortaliA0LPA9.
SMRiA0LPA9. Positions 13-549.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiRAHYVSN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0LPA9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLRKQDPMKT AGWKKLSDHF QTMKDVHMRD LFAEDGDRFQ RFSIRFGDIL
60 70 80 90 100
VDYSKNRLNQ ETLLLLLGLA EEVGLKDGVE AMFTGERINE TEDRAVLHTA
110 120 130 140 150
LRNRSDAPVF VDGRDVMPEV NAVLKKMEEF SRRVISGRWK GYSGKPVRDI
160 170 180 190 200
VNIGIGGSDL GPKMVAECLR PYAAKGLSVH FVSNVDGTHI VETLKLLDPE
210 220 230 240 250
TTLFMIASKT FTTQETMTNA HTARDWFLKH AGDPAHIARH FVALSTNTDR
260 270 280 290 300
VKAFGIDPEN MFVFWDWVGG RYSLWSAIGL SVACAIGFEG FLDLLQGAHE
310 320 330 340 350
MDRHFREEPF ERNIPVILAL IGIWYNNFFG AESEAVLPYD QYMHRFPAYF
360 370 380 390 400
QQGNMESNGK SADRGGGRVR HQTGPIIWGE PGTNGQHAFY QLIHQGTKLV
410 420 430 440 450
PADFLAPALS HNDVGDHHAI LLSNFFAQTE ALMRGKNREE VIEELRREGR
460 470 480 490 500
SEDAIQRLWP HKVFEGNKPT NSILFRKLTP RVLGSLIAMY EHKIFVQGVI
510 520 530 540 550
WNIFSFDQWG VELGKQLAAR ILPELNDRTT VAAHDSSTNG LINAYKQMRG
Length:550
Mass (Da):62,258
Last modified:December 12, 2006 - v1
Checksum:i601E6A67DF1981C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000478 Genomic DNA. Translation: ABK19261.1.
RefSeqiYP_847696.1. NC_008554.1.

Genome annotation databases

EnsemblBacteriaiABK19261; ABK19261; Sfum_3591.
GeneIDi4458082.
KEGGisfu:Sfum_3591.
PATRICi23853441. VBISynFum78438_4273.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000478 Genomic DNA. Translation: ABK19261.1 .
RefSeqi YP_847696.1. NC_008554.1.

3D structure databases

ProteinModelPortali A0LPA9.
SMRi A0LPA9. Positions 13-549.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 335543.Sfum_3591.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK19261 ; ABK19261 ; Sfum_3591 .
GeneIDi 4458082.
KEGGi sfu:Sfum_3591.
PATRICi 23853441. VBISynFum78438_4273.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi RAHYVSN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci SFUM335543:GH6P-3646-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10017 / MPOB.

Entry informationi

Entry nameiG6PI_SYNFM
AccessioniPrimary (citable) accession number: A0LPA9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: November 26, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3