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Protein

NAD(P)H dehydrogenase (quinone)

Gene

Sfum_3387

Organism
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei11NAD(P)UniRule annotation1
Binding sitei102SubstrateUniRule annotation1
Binding sitei138FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 14FMNUniRule annotation6
Nucleotide bindingi82 – 84FMNUniRule annotation3

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciSFUM335543:G1G7I-3498-MONOMER

Protein family/group databases

CAZyiAA6 Auxiliary Activities 6

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:Sfum_3387
OrganismiSyntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Taxonomic identifieri335543 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophobacteraceaeSyntrophobacter
Proteomesi
  • UP000001784 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002910331 – 204NAD(P)H dehydrogenase (quinone)Add BLAST204

Interactioni

Protein-protein interaction databases

STRINGi335543.Sfum_3387

Structurei

3D structure databases

ProteinModelPortaliA0LNQ8
SMRiA0LNQ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 194Flavodoxin-likeUniRule annotationAdd BLAST192

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CS1 Bacteria
COG0655 LUCA
HOGENOMiHOG000030539
KOiK03809
OMAiVGVPYAC
OrthoDBiPOG091H03V0

Family and domain databases

Gene3Di3.40.50.3601 hit
HAMAPiMF_01017 NQOR, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR029039 Flavoprotein-like_sf
IPR010089 Flavoprotein_WrbA-like
IPR005025 FMN_Rdtase-like
IPR037513 NQO
PfamiView protein in Pfam
PF03358 FMN_red, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01755 flav_wrbA, 1 hit
PROSITEiView protein in PROSITE
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

A0LNQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLIVFYSM YGHIYRMAEA VAEGVRSVDG AEAVLRRVPE TLSAEILASM
60 70 80 90 100
GATEAQKQFA HIPVCTVDEL GAADAVIFGT PTRFGNMAGQ MRQFLDATGR
110 120 130 140 150
LWVSGALVGK AGSVFTSSNT QHGGQESTIL SFHINLLHQG MVIVGLPYSF
160 170 180 190 200
QGQSTMDEIT GGSPYGASTI AGPTGARTPS DNELAGARYQ GRHVAEIARK

LTRN
Length:204
Mass (Da):21,679
Last modified:December 12, 2006 - v1
Checksum:iD1B54E01F57531A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000478 Genomic DNA Translation: ABK19060.1
RefSeqiWP_011700185.1, NC_008554.1

Genome annotation databases

EnsemblBacteriaiABK19060; ABK19060; Sfum_3387
KEGGisfu:Sfum_3387

Similar proteinsi

Entry informationi

Entry nameiNQOR_SYNFM
AccessioniPrimary (citable) accession number: A0LNQ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: December 12, 2006
Last modified: February 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome