A0LIM7 (TATA_SYNFM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sec-independent protein translocase protein TatA

Gene names

Name:	tatA
Ordered Locus Names:	Sfum_1592

Organism

Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) [Complete proteome] [HAMAP]

Taxonomic identifier

335543 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Syntrophobacterales › Syntrophobacteraceae › Syntrophobacter

Protein attributes

Sequence length	64 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system By similarity. HAMAP MF_00236
Subunit structure	The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon By similarity.
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity HAMAP MF_00236.
Sequence similarities	Belongs to the TatA/E family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein secretion Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	protein transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 64	64	Sec-independent protein translocase protein TatA HAMAP MF_00236		PRO_1000058971
Regions
	Transmembrane	1 – 21	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	A0LIM7 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: C93D8B5BFDE7A5B5	FASTA	64	6,762
	10 20 30 40 50 60 MIGGIGMPEL IVILVIVLII FGAGRLPELG AGLGKGIKNF RKATSELESA ATGEKKPEEL EEKK

References

[1]

"Complete sequence of Syntrophobacter fumaroxidans MPOB." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G., Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Boone D.R. , Brockman F., Culley D., Ferry J., Gunsalus R., McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J., Sieber J., Stams A.J.M., Worm P., Henstra A.M., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 10017 / MPOB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000478 Genomic DNA. Translation: ABK17279.1.
RefSeq	YP_845714.1. NC_008554.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0LIM7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4460127.
GenomeReviews	Gene locus Sfum_1592 in contig CP000478_GR.
KEGG	sfu:Sfum_1592.
NMPDR	fig|335543.6.peg.1640.
PATRIC	23848565. VBISynFum78438_1856.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG751935.
OMA	ILFGGQK.
ProtClustDB	PRK14859.
Enzyme and pathway databases
BioCyc	SFUM335543:SFUM_1592-MONOMER.
Family and domain databases
HAMAP	MF_00236. TatA_E. [Tree]
InterPro	IPR003369. TatA/B/E. IPR006312. TatA_E. IPR003998. TatB-like. [Graphical view]
KO	K03116.
Pfam	PF02416. MttA_Hcf106. 1 hit. [Graphical view]
PRINTS	PR01506. TATBPROTEIN.
TIGRFAMs	TIGR01411. TatAE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TATA_SYNFM

Accession

Primary (citable) accession number: A0LIM7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	December 12, 2006
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program