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A0LG71 (UPPP_SYNFM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Sfum_0725
OrganismSyntrophobacter fumaroxidans (strain DSM 10017 / MPOB) [Complete proteome] [HAMAP]
Taxonomic identifier335543 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophobacteraceaeSyntrophobacter

Protein attributes

Sequence length281 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 281281Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290776

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane93 – 11321Helical; Potential
Transmembrane125 – 14521Helical; Potential
Transmembrane155 – 17521Helical; Potential
Transmembrane195 – 21521Helical; Potential
Transmembrane227 – 24721Helical; Potential
Transmembrane256 – 27621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A0LG71 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: B311D3F57C17F326

FASTA28130,725
        10         20         30         40         50         60 
MNVLQGLLLG LIQGLTEFLP ISSTAHLTLA GKWMGVVSAE HPEHWTAFIA VIQLGTMAAV 

        70         80         90        100        110        120 
LIYFARDVLD ISLTFLEENV FRRMRFKDQS HVSKLGWYVI LGSLPVATFG LVFKKVIEGS 

       130        140        150        160        170        180 
LTKSLIVISA SLIVFGILLG VSEVVARFSK SIKRISWLDA LVVGFAQVMA LVPGASRSGT 

       190        200        210        220        230        240 
TITAGLFMGM TRETAARFSF LLSIPAVMAS GLLEFRESLD FMGSQDFLVL ASATLMSAVS 

       250        260        270        280 
GYLTIAFLLR FLRRHSTNVF VVYRVVLGGA LLWMVFRHGV V 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000478 Genomic DNA. Translation: ABK16423.1.
RefSeqYP_844858.1. NC_008554.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING335543.Sfum_0725.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK16423; ABK16423; Sfum_0725.
GeneID4460791.
KEGGsfu:Sfum_0725.
PATRIC23846509. VBISynFum78438_0844.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMALVGCFQC.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycSFUM335543:GH6P-742-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_SYNFM
AccessionPrimary (citable) accession number: A0LG71
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: December 12, 2006
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families