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A0LG58

- A0LG58_SYNFM

UniProt

A0LG58 - A0LG58_SYNFM

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Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Sfum_0712

Organism
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Note: Binds 2 magnesium or manganese ions per subunit.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  3. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSFUM335543:GH6P-729-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:Sfum_0712Imported
OrganismiSyntrophobacter fumaroxidans (strain DSM 10017 / MPOB)Imported
Taxonomic identifieri335543 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophobacteraceaeSyntrophobacter
ProteomesiUP000001784: Chromosome

Subcellular locationi

Cytoplasm SAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi335543.Sfum_0712.

Structurei

3D structure databases

ProteinModelPortaliA0LG58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG1181.
HOGENOMiHOG000011592.
KOiK01921.
OMAiFLEVNPL.
OrthoDBiEOG66MQKK.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0LG58-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVGIAYDLR QEYLAEGYSD EETAEFDRPE TIDAIESALR DLKFETDRIG
60 70 80 90 100
HVRNLVRRLA VGERWDLVFN IAEGLAGFGR EAAIPALLDA YGIPYTFSDP
110 120 130 140 150
LVLSLSLHKG MAKNVLRNMG IPTADFVVIQ DVSETEAIGI PFPVFAKPVA
160 170 180 190 200
EGTGKGIDAA SRIGTQEELV AKCRQLLEVY RQPVLIEKFL PGREFTVGLV
210 220 230 240 250
GTGAKTEVVG VMEVILKDGA ERDAYSYSNK EHYERRVEYR LAEGSIARLA
260 270 280 290 300
ARISVEAWRK LGCRDGGRID LRCDERNVPS FVELNPLAGL HPVHSDLPIL
310 320
SRLAGMSYVE LIGRIMASAM ERVDSG
Length:326
Mass (Da):36,025
Last modified:December 12, 2006 - v1
Checksum:iF3F5091B2A58DE04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000478 Genomic DNA. Translation: ABK16410.1.
RefSeqiYP_844845.1. NC_008554.1.

Genome annotation databases

EnsemblBacteriaiABK16410; ABK16410; Sfum_0712.
GeneIDi4461274.
KEGGisfu:Sfum_0712.
PATRICi23846483. VBISynFum78438_0831.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000478 Genomic DNA. Translation: ABK16410.1 .
RefSeqi YP_844845.1. NC_008554.1.

3D structure databases

ProteinModelPortali A0LG58.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 335543.Sfum_0712.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK16410 ; ABK16410 ; Sfum_0712 .
GeneIDi 4461274.
KEGGi sfu:Sfum_0712.
PATRICi 23846483. VBISynFum78438_0831.

Phylogenomic databases

eggNOGi COG1181.
HOGENOMi HOG000011592.
KOi K01921.
OMAi FLEVNPL.
OrthoDBi EOG66MQKK.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci SFUM335543:GH6P-729-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10017 / MPOBImported.

Entry informationi

Entry nameiA0LG58_SYNFM
AccessioniPrimary (citable) accession number: A0LG58
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: November 26, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3