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Protein

Adenine deaminase

Gene

ade

Organism
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciSFUM335543:GH6P-424-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Sfum_0417
OrganismiSyntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Taxonomic identifieri335543 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophobacteraceaeSyntrophobacter
Proteomesi
  • UP000001784 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 576576Adenine deaminasePRO_0000292401Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi335543.Sfum_0417.

Structurei

3D structure databases

ProteinModelPortaliA0LFB5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

A0LFB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWDTGRMAR IIEAAQGKRV VDLCIRRCRL VNVLSGSIDT VDLAIHEGFV
60 70 80 90 100
AGWGSYRAAR EIDADGMYVC PGFIDGHIHI ESTLLAPAQF CAAAVPQGTA
110 120 130 140 150
AVVADPHEIA NVLGLSGIRY FLEASEGLPL DFFFNLPSCV PATPLETSGA
160 170 180 190 200
ALRAPDLDAL LPHERLIGLA EMMNFPGVLS GFPDVIDKLL LFQARRIDGH
210 220 230 240 250
APQLGDLGLN AYVAAGITSD HECTTLEEAR EKLAKGMTVM IREGGQSRDL
260 270 280 290 300
AALLPAVDEH TWPRCCFVSD DVHPDGLLRE GHMNVIVNRA MSLGMAPVRA
310 320 330 340 350
LSLAALTPAR HFRLDRRGAL APGYHADFSM SPTLNPWQPE RVFKAGVEVA
360 370 380 390 400
RDGRLLLDLG NGNGVAAPPS PMHITRLLAE DLVVPAQPGL LRIIGVREGT
410 420 430 440 450
LLTRKIVLPP KIHEGAAVAD LDRDILKLAV YNRYVPDRPP AVAFVQGLGL
460 470 480 490 500
KEGAIATTVA HDSHNLIVAG ASDADILHVV DAVRKSGGGM AAGRTGAEVD
510 520 530 540 550
VLALPIAGLM SDQPVERVAE RLEQLQGRAR AAGSGLRNPF MALSFLALPV
560 570
IPELKLTDLG LIDVSTFSPV SLFETS
Length:576
Mass (Da):61,529
Last modified:December 12, 2006 - v1
Checksum:iF8593358977B12E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000478 Genomic DNA. Translation: ABK16117.1.

Genome annotation databases

EnsemblBacteriaiABK16117; ABK16117; Sfum_0417.
KEGGisfu:Sfum_0417.
PATRICi23845775. VBISynFum78438_0486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000478 Genomic DNA. Translation: ABK16117.1.

3D structure databases

ProteinModelPortaliA0LFB5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi335543.Sfum_0417.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK16117; ABK16117; Sfum_0417.
KEGGisfu:Sfum_0417.
PATRICi23845775. VBISynFum78438_0486.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciSFUM335543:GH6P-424-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10017 / MPOB.

Entry informationi

Entry nameiADEC_SYNFM
AccessioniPrimary (citable) accession number: A0LFB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 12, 2006
Last modified: November 11, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.