A0LDX4 (ARGB_MAGSM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	Mmc1_3682

Organism

Magnetococcus sp. (strain MC-1) [Complete proteome] [HAMAP]

Taxonomic identifier

156889 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Magnetococcus

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC glutamate 5-kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 294	294	Acetylglutamate kinase HAMAP MF_00082_B		PRO_0000335643
Regions
	Region	66 – 67	2	Substrate binding By similarity
Sites
	Binding site	88	1	Substrate By similarity
	Binding site	193	1	Substrate By similarity
	Site	31	1	Transition state stabilizer By similarity
	Site	253	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0LDX4 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 417B75B3C619A170	FASTA	294	31,863
	10 20 30 40 50 60 MPMRNQVEKV KVLIEALPYM RRFEGKTFVI KYGGNAMVDE DLKSAFAQDV ILMRQVGINP 70 80 90 100 110 120 IIVHGGGPQI GLIMKRMGLE PKFIDGLRVT DEDTMSVVEM VLAGKVNKDI VNLINLNGGR 130 140 150 160 170 180 AAGLSGKDGY TIQARKRTHV RKGPDVQVPE IIDLGWVGDV ERIETNLLDR FRASDIIPVV 190 200 210 220 230 240 APVGVGANGE TYNINADSVA GHIAIAMQAE KLILLTDVPG VQDKNGTLIN QIDETDVDKL 250 260 270 280 290 IRNGTVTGGM IPKLETCRTA HTGGVNASHI IDGRVEHALL LEIFTDSGIG TVLR

References

[1]

"Complete sequence of Magnetococcus sp. MC-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Goodwin L.A., Brettin T., Bruce D., Han C., Tapia R., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MC-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000471 Genomic DNA. Translation: ABK46167.1.
RefSeq	YP_867573.1. NC_008576.1.
3D structure databases
ProteinModelPortal	A0LDX4.
SMR	A0LDX4. Positions 5-294.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LDX4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4480962.
GenomeReviews	Gene locus Mmc1_3682 in contig CP000471_GR.
KEGG	mgm:Mmc1_3682.
NMPDR	fig|156889.1.peg.3095.
PATRIC	22434097. VBIMagSp23654_3766.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0548.
HOGENOM	HBG497643.
OMA	GGNAMID.
PhylomeDB	A0LDX4.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. IPR001057. Glu/AcGlu_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
PRINTS	PR00474. GLU5KINASE.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_MAGSM

Accession

Primary (citable) accession number: A0LDX4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program