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A0LDR4

- NUON_MAGSM

UniProt

A0LDR4 - NUON_MAGSM

Protein

NADH-quinone oxidoreductase subunit N

Gene

nuoN

Organism
Magnetococcus sp. (strain MC-1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.UniRule annotation

    Catalytic activityi

    NADH + quinone = NAD+ + quinol.UniRule annotation

    GO - Molecular functioni

    1. NADH dehydrogenase (ubiquinone) activity Source: InterPro
    2. quinone binding Source: UniProtKB-KW

    GO - Biological processi

    1. ATP synthesis coupled electron transport Source: InterPro
    2. transport Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    NAD, Ubiquinone

    Enzyme and pathway databases

    BioCyciMSP156889:GH36-3670-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH-quinone oxidoreductase subunit NUniRule annotation (EC:1.6.99.5UniRule annotation)
    Alternative name(s):
    NADH dehydrogenase I subunit NUniRule annotation
    NDH-1 subunit NUniRule annotation
    Gene namesi
    Name:nuoNUniRule annotation
    Ordered Locus Names:Mmc1_3622
    OrganismiMagnetococcus sp. (strain MC-1)
    Taxonomic identifieri156889 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus
    ProteomesiUP000002586: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 483483NADH-quinone oxidoreductase subunit NPRO_0000391174Add
    BLAST

    Keywords - PTMi

    Quinone

    Interactioni

    Subunit structurei

    NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi156889.Mmc1_3622.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei8 – 2821HelicalUniRule annotationAdd
    BLAST
    Transmembranei45 – 6521HelicalUniRule annotationAdd
    BLAST
    Transmembranei78 – 9821HelicalUniRule annotationAdd
    BLAST
    Transmembranei106 – 12621HelicalUniRule annotationAdd
    BLAST
    Transmembranei131 – 15121HelicalUniRule annotationAdd
    BLAST
    Transmembranei166 – 18621HelicalUniRule annotationAdd
    BLAST
    Transmembranei206 – 22621HelicalUniRule annotationAdd
    BLAST
    Transmembranei241 – 26121HelicalUniRule annotationAdd
    BLAST
    Transmembranei275 – 29521HelicalUniRule annotationAdd
    BLAST
    Transmembranei303 – 32321HelicalUniRule annotationAdd
    BLAST
    Transmembranei330 – 35021HelicalUniRule annotationAdd
    BLAST
    Transmembranei373 – 39321HelicalUniRule annotationAdd
    BLAST
    Transmembranei399 – 41921HelicalUniRule annotationAdd
    BLAST
    Transmembranei452 – 47221HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I subunit 2 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1007.
    HOGENOMiHOG000100795.
    KOiK00343.
    OMAiMVSSNHL.
    OrthoDBiEOG64JFNZ.

    Family and domain databases

    HAMAPiMF_00445. NDH1_NuoN_1.
    InterProiIPR010096. NADH-Q_OxRdtase_suN/2.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    [Graphical view]
    PfamiPF00361. Oxidored_q1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01770. NDH_I_N. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A0LDR4-1 [UniParc]FASTAAdd to Basket

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    MAIQMPDINL ALMLPEIVIS VVAMGLLLAS AWWEGAEGAR RIRRIAAGAL    50
    MVAMVITLLG VGATQSSTFG GMFVNDRFAA FMKVMLYLST LLPMVVSWVY 100
    LEKSKLGNGE YFVLTLFAML GGMFMISSGS FLVLYLGIEL LSLAIYVLAA 150
    YKRDDLASNE AGLKYFVLGS MASGILLYGI SLIYGVTGSV DFATINAYLQ 200
    QDHHSMLGIT MGLILVVSGL SFKIAAAPFH MWAPDVYEGA PTSVTAFMAA 250
    MPKIAAFAAL FRVLVEAFGP MHATWGPIMA LLAVVSMGVG ALAGLGQSNI 300
    KRLLAYSSIG HVGYALIGLA VGNQMGYEAV LVYLTIYIFM NVGAFGLILV 350
    LNKEGFGDQI EDYKGLSAKR PGLALLMAIF MFSMAGIPPL AGFMAKLQIF 400
    MAAIDAHMYT VAILGVLFSA VSAFYYLKVI KTMYFDEAER AFDMPMDFLS 450
    RAIVGVSGIL VVLWGILPGS LMASVAETIK SLM 483
    Length:483
    Mass (Da):51,796
    Last modified:December 12, 2006 - v1
    Checksum:i6D2C95DEA196F801
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000471 Genomic DNA. Translation: ABK46107.1.
    RefSeqiYP_867513.1. NC_008576.1.

    Genome annotation databases

    EnsemblBacteriaiABK46107; ABK46107; Mmc1_3622.
    GeneIDi4480522.
    KEGGimgm:Mmc1_3622.
    PATRICi22433961. VBIMagSp23654_3705.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000471 Genomic DNA. Translation: ABK46107.1 .
    RefSeqi YP_867513.1. NC_008576.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 156889.Mmc1_3622.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK46107 ; ABK46107 ; Mmc1_3622 .
    GeneIDi 4480522.
    KEGGi mgm:Mmc1_3622.
    PATRICi 22433961. VBIMagSp23654_3705.

    Phylogenomic databases

    eggNOGi COG1007.
    HOGENOMi HOG000100795.
    KOi K00343.
    OMAi MVSSNHL.
    OrthoDBi EOG64JFNZ.

    Enzyme and pathway databases

    BioCyci MSP156889:GH36-3670-MONOMER.

    Family and domain databases

    HAMAPi MF_00445. NDH1_NuoN_1.
    InterProi IPR010096. NADH-Q_OxRdtase_suN/2.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    [Graphical view ]
    Pfami PF00361. Oxidored_q1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01770. NDH_I_N. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MC-1.

    Entry informationi

    Entry nameiNUON_MAGSM
    AccessioniPrimary (citable) accession number: A0LDR4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 9, 2010
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3