A0LDN6 (A0LDN6_MAGSM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase HAMAP MF_01023

Gene names

Name:	hisC HAMAP MF_01023
Ordered Locus Names:	Mmc1_3594

Organism

Magnetococcus sp. (strain MC-1) [Complete proteome] [HAMAP]

Taxonomic identifier

156889 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Magnetococcus

Protein attributes

Sequence length	365 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861
Ligand	Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL ABK46079.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	221	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	A0LDN6 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 8F4D9AF1568BD5A2	FASTA	365	40,144
	10 20 30 40 50 60 MDHDMSVQQW VRPEILAMAG YTPGEQPKPG EQVIKLNTNE NPYGPPEAVK QAMHAAIHDN 70 80 90 100 110 120 LRRYPSPDGY GVREAAARVL GHGLTPEQII LGNGSDDLLT MLLRTFIDPG QVVASMEPTY 130 140 150 160 170 180 TLYEALVTIQ GGCYRSVPWQ PDGGLPLEGL VALQPKLIFV TRPNAPTGHV VPLEQVAALC 190 200 210 220 230 240 QAVAQSAVVV LDEAYGDFAE DHGLPLLAAH PNLIITRSAS KSLSLAGMRI GIGFMHADVA 250 260 270 280 290 300 LQMHKVRDSY NVDRVAQAAL LAAYENWSDY APLIARIKQQ RQWTTTQLRK RGFEVKDSYG 310 320 330 340 350 360 NFVLARVPQG GLDGLQWLES LKKRGILIRY FGSIPQLSEF LRITIGTEEE MALLMTAIDE IMKVA

References

[1]

"Complete sequence of Magnetococcus sp. MC-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Goodwin L.A., Brettin T., Bruce D., Han C., Tapia R., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MC-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000471 Genomic DNA. Translation: ABK46079.1.
RefSeq	YP_867485.1. NC_008576.1.
3D structure databases
ProteinModelPortal	A0LDN6.
ModBase	Search...
Protein-protein interaction databases
STRING	A0LDN6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4483765.
GenomeReviews	Gene locus Mmc1_3594 in contig CP000471_GR.
KEGG	mgm:Mmc1_3594.
NMPDR	fig|156889.1.peg.2542.
PATRIC	22433895. VBIMagSp23654_3672.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0079.
HOGENOM	HBG646350.
OMA	QMDKVRD.
PhylomeDB	A0LDN6.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0LDN6_MAGSM

Accession

Primary (citable) accession number: A0LDN6

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)