ID   A0LB38_MAGMM            Unreviewed;      1093 AA.
AC   A0LB38;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABK45181.1};
GN   OrderedLocusNames=Mmc1_2685 {ECO:0000313|EMBL:ABK45181.1};
OS   Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Magnetococcales;
OC   Magnetococcaceae; Magnetococcus.
OX   NCBI_TaxID=156889 {ECO:0000313|EMBL:ABK45181.1, ECO:0000313|Proteomes:UP000002586};
RN   [1] {ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=19465526; DOI=10.1128/AEM.02874-08;
RA   Schubbe S., Williams T.J., Xie G., Kiss H.E., Brettin T.S., Martinez D.,
RA   Ross C.A., Schuler D., Cox B.L., Nealson K.H., Bazylinski D.A.;
RT   "Complete genome sequence of the chemolithoautotrophic marine magnetotactic
RT   coccus strain MC-1.";
RL   Appl. Environ. Microbiol. 75:4835-4852(2009).
RN   [2] {ECO:0000313|EMBL:ABK45181.1, ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=22581902;
RA   Bazylinski D.A., Williams T.J., Lefevre C.T., Berg R.J., Zhang C.L.,
RA   Bowser S.S., Dean A.J., Beveridge T.J.;
RT   "Magnetococcus marinus gen. nov., sp. nov., a marine, magnetotactic
RT   bacterium that represents a novel lineage (Magnetococcaceae fam. nov.;
RT   Magnetococcales ord. nov.) at the base of the Alphaproteobacteria.";
RL   Int. J. Syst. Evol. Microbiol. 0:0-0(2012).
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DR   EMBL; CP000471; ABK45181.1; -; Genomic_DNA.
DR   RefSeq; WP_011714280.1; NC_008576.1.
DR   AlphaFoldDB; A0LB38; -.
DR   STRING; 156889.Mmc1_2685; -.
DR   KEGG; mgm:Mmc1_2685; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG3899; Bacteria.
DR   HOGENOM; CLU_004435_4_0_5; -.
DR   OrthoDB; 341967at2; -.
DR   Proteomes; UP000002586; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR025874; DZR.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF12773; DZR; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002586};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          93..225
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REPEAT          800..833
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   1093 AA;  121801 MW;  F02307827E083CB5 CRC64;
     MGCLDCGFDN REGVRFCTQC GLPQAAFCPR CHFAAAEGDR FCGGCGLRLQ MGQGVLPSSE
     GGAGKLLTAV SASSGKGVLP ANQSMESERK HVTVLFADIS GFTAMSEKLD PEEVTQIMNG
     CLKMLADVVT HYEGYVDKFI GDCIMALFGA PVTHENDPEL ALRAALDMQQ GMLNYNKNLP
     VKLDKPLTLH IGINTGIVIA GGVGSDQKME YTVMGDTVNL ASRLESKAAS GETFLSGYTY
     NMTRSLFEFD RLEPMMVKGK QKPVEVYRLK GLNRGRGDDR KAHLPLVGRA EEMRQLSERV
     ERLVEGKGQV VFLTSEQGFG KSRIRLEIRK QLVDMGLTLL EGACHSFCRS TRYHVVGELL
     KQLFGINADD GDAVALENME AALTTLLELP PDLNQESARA LVYIASLLGL KVDNQRYEIP
     LEQMDPREVK AETFRAIAWL FTKMAKKRPL VITVEDLDNA DSASMELLTF LLEDLRSVPV
     MFLLLMRAGG ERDASKLTTT CKRVWGADFL EVAFSQFSEE ECGLLIQHLL GSHQIPAELY
     SLVMNRTDGN PLFIEEVVQS LVDGQVVEKR SDGSIGLLKD LAGVSIPGSV HSLILARIDK
     LQTKLKDLLQ MASVIGNVFR LDLLQAAFPV ADLDQRLRLL EEMGILYEVR SFPEVEYSFR
     NGLIQEAVYA TMLKQKVREL HLKVADLTET LYAERLENHL ESLARHLELA QAWPRAYRYL
     VRSGDKARLA FANLEAKGYY QRTVEVAEQN PEVLAQAEAP SLAQVYTHLS EVEELLGDMD
     AAIKAREHGV TLLDSAVEKA AETRLIGRLL EKRGDKEQAL EVYDRAVELL AGFPDHVEMG
     RVLTNRSWVL NRMKQGARAL HEAQTAMQIF QAHDARGDMA LLYNNLSVFC EHAGDLEQAL
     AHNQKSLQMF EALGNVRQQG NVHLSLGYIY NGLRNFEQAL IHFDQSFELM DRIGNRYGAA
     TALMSKGRCL LDVDKVEEGE TALLRALRIH KELNISRKVV ANQLALVRLY LRNVDHHAAR
     RFLSEAKELA RREGFESDLA KLAQLEGDLM VLEGKDPCGQ YQEAISLFGA MGRTREAEQV
     IKALERYRSS NHQ
//