ID   A0LAQ0_MAGMM            Unreviewed;       712 AA.
AC   A0LAQ0;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABK45043.1};
GN   OrderedLocusNames=Mmc1_2543 {ECO:0000313|EMBL:ABK45043.1};
OS   Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Magnetococcales;
OC   Magnetococcaceae; Magnetococcus.
OX   NCBI_TaxID=156889 {ECO:0000313|EMBL:ABK45043.1, ECO:0000313|Proteomes:UP000002586};
RN   [1] {ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=19465526; DOI=10.1128/AEM.02874-08;
RA   Schubbe S., Williams T.J., Xie G., Kiss H.E., Brettin T.S., Martinez D.,
RA   Ross C.A., Schuler D., Cox B.L., Nealson K.H., Bazylinski D.A.;
RT   "Complete genome sequence of the chemolithoautotrophic marine magnetotactic
RT   coccus strain MC-1.";
RL   Appl. Environ. Microbiol. 75:4835-4852(2009).
RN   [2] {ECO:0000313|EMBL:ABK45043.1, ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=22581902;
RA   Bazylinski D.A., Williams T.J., Lefevre C.T., Berg R.J., Zhang C.L.,
RA   Bowser S.S., Dean A.J., Beveridge T.J.;
RT   "Magnetococcus marinus gen. nov., sp. nov., a marine, magnetotactic
RT   bacterium that represents a novel lineage (Magnetococcaceae fam. nov.;
RT   Magnetococcales ord. nov.) at the base of the Alphaproteobacteria.";
RL   Int. J. Syst. Evol. Microbiol. 0:0-0(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC       {ECO:0000256|ARBA:ARBA00005381}.
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DR   EMBL; CP000471; ABK45043.1; -; Genomic_DNA.
DR   RefSeq; WP_011714162.1; NC_008576.1.
DR   AlphaFoldDB; A0LAQ0; -.
DR   STRING; 156889.Mmc1_2543; -.
DR   KEGG; mgm:Mmc1_2543; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_021956_0_0_5; -.
DR   OrthoDB; 9762462at2; -.
DR   Proteomes; UP000002586; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002586};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          371..424
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          451..583
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   712 AA;  79714 MW;  5202A9F32C2EE8D8 CRC64;
     MMHNRQVELR IGISLAFGLV MALLTVSLVG YLYWDNSKLI LETASKTMAR ATLQVDRDVQ
     GLLAPVERVV QATAELARVD TGSLQTVQGL GYLQRQLVSL PQVFSFYLGF ENSGDFYQVF
     AVPPTLKQLG PSKEDLPQGV RYAARLLNES SGHRADSFIF YKEWGDVVKV DRGPVRYDPR
     VRPWYKKAWE VPQVAISDAY VFASSKLIGL TLSSHVSTPS DIKIGVVGAD ITLDTLSSFL
     YKAQIGLSGR VFLLNADNYL VGHREPDMGV EVTEEKVRLR KATEVRDPLV AEAVQHWQKS
     GVDRFETTLG PNGDEYMVSF AKIGGSLGWT AGVLVQKEEL IGPLADASIK ILVAGSLAIS
     LAIFLFMMLS QLLTRPLSKV TQETVKIRRF NLEGNLNLTS YISEVRQLVD AVETMKRSLR
     SFSVYVPKEI VRAIVEDEDE TSIGSRRQPL TVMFSDIKGF SNISEELPPE QLVGSLSEYM
     EQMSQPIHRY KGTIDKFIGD AIMALWNAPS KDPDHVVNAC RAMLGCHRAG LALAETFAKN
     GRTPFYTRFG LHTGEAVVGN VGSTERMQYS AFGNMVNMAS RLESMNKQYD TELMVSEHVA
     RVAQPHFYLR RLDKVVPVGN THPMYVYELM GEKDPKSPLA ATEEQKLKLS LWHAVMDHYE
     ARDWHAVLEK LALYKQSFPH DKGAEQIEKR CHLFIVTPPP ADWDGAEWLK NK
//