SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0LA23

- PUR5_MAGSM

UniProt

A0LA23 - PUR5_MAGSM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, Mmc1_2316
Organism
Magnetococcus sp. (strain MC-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMSP156889:GH36-2349-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:Mmc1_2316
OrganismiMagnetococcus sp. (strain MC-1)
Taxonomic identifieri156889 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus
ProteomesiUP000002586: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 353353Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_1000046444Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi156889.Mmc1_2316.

Structurei

3D structure databases

ProteinModelPortaliA0LA23.
SMRiA0LA23. Positions 11-352.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

A0LA23-1 [UniParc]FASTAAdd to Basket

« Hide

MAHNQDASSP SGMTYRDAGV DIDAGNRLVS MIKRSVASTH RPEVRSDLGG    50
FGALFDLDTR KYQDPVLVSA TDGVGTKLKL AFLTGKHDTV GIDLVAMSVN 100
DLVVQGAEPL FFLDYFACGK LSPETAATVV EGIATGCRAA GCALIGGETA 150
EMPGFYTEGE YDLAGFAVGA VDKHKIIDGR HISPGDAIIG LASSGPHSNG 200
YSLIRKLVLG QSGPGLEADF NGKPLGEVLL TPTHIYVLPL LELAKTHAIH 250
GLVHITGGGF WENIPRILPD ATGALLKRSC WQQPEVFNLL QKLGNIAEDE 300
MLRTFNCGLG MLVIVPATQA DSALAQLRAA GEQAELVGEI TSCKEGDARV 350
VIL 353
Length:353
Mass (Da):37,219
Last modified:December 12, 2006 - v1
Checksum:iF9F965CA698AABEB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44816.1.
RefSeqiYP_866222.1. NC_008576.1.

Genome annotation databases

EnsemblBacteriaiABK44816; ABK44816; Mmc1_2316.
GeneIDi4480936.
KEGGimgm:Mmc1_2316.
PATRICi22431255. VBIMagSp23654_2368.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44816.1 .
RefSeqi YP_866222.1. NC_008576.1.

3D structure databases

ProteinModelPortali A0LA23.
SMRi A0LA23. Positions 11-352.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 156889.Mmc1_2316.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK44816 ; ABK44816 ; Mmc1_2316 .
GeneIDi 4480936.
KEGGi mgm:Mmc1_2316.
PATRICi 22431255. VBIMagSp23654_2368.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci MSP156889:GH36-2349-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC-1.

Entry informationi

Entry nameiPUR5_MAGSM
AccessioniPrimary (citable) accession number: A0LA23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi