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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMMAR156889:G1G7E-2323-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:Mmc1_2217
OrganismiMagnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)
Taxonomic identifieri156889 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus
Proteomesi
  • UP000002586 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003664681 – 369Ribosomal RNA large subunit methyltransferase GAdd BLAST369

Interactioni

Protein-protein interaction databases

STRINGi156889.Mmc1_2217

Structurei

3D structure databases

ProteinModelPortaliA0L9S5
SMRiA0L9S5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J Bacteria
COG2813 LUCA
HOGENOMiHOG000246323
KOiK11391
OMAiNLQAWDA
OrthoDBiPOG091H05RK

Family and domain databases

HAMAPiMF_01859 23SrRNA_methyltr_G, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR017237 rRNA_m2G-MeTrfase_RsmD
IPR029063 SAM-dependent_MTases
IPR007848 Small_mtfrase_dom
PANTHERiPTHR18895:SF6 PTHR18895:SF6, 2 hits
PfamiView protein in Pfam
PF05175 MTS, 1 hit
PIRSFiPIRSF037565 RRNA_m2G_Mtase_RsmD_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

A0L9S5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQHLNIHGHT LTLRRFPHKP GCPLQAWDAA DALALTNHAL PDGEILILND
60 70 80 90 100
HFGALACGLA YPERTLEWVN DSYMAHQALA QNLQLNRIET PLHRTPALAA
110 120 130 140 150
SPTNPVGILI KLPRMLQLLS SQLDWLNLHL PKGTPVVIAA RQKDMPSTLP
160 170 180 190 200
DLTRRLLDDV HPSRAEKKAR LIFGQLSGRQ SGQAEITAWH CAELDCLLSH
210 220 230 240 250
YPNVFGRQKL DLGARVLLQN LGTIPDQVVD LGCGNGVLSI AALQRNPNSH
260 270 280 290 300
VLAVDESWQA TRSCQINLER VRTPEHFKVV WGHSLSFIEG MQADLVLCNP
310 320 330 340 350
PFHQHQTLTD DIAWCMFKDA HRVLKPGGRL RMVGNRHLGY HAKLHKLFGH
360
CRSIAATPKF VVLESVKSS
Length:369
Mass (Da):41,088
Last modified:December 12, 2006 - v1
Checksum:i239E4BB8E1866100
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000471 Genomic DNA Translation: ABK44718.1
RefSeqiWP_011713839.1, NC_008576.1

Genome annotation databases

EnsemblBacteriaiABK44718; ABK44718; Mmc1_2217
KEGGimgm:Mmc1_2217

Similar proteinsi

Entry informationi

Entry nameiRLMG_MAGMM
AccessioniPrimary (citable) accession number: A0L9S5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: December 12, 2006
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health