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A0L9F4 (UPPP_MAGSM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Mmc1_2096
OrganismMagnetococcus sp. (strain MC-1) [Complete proteome] [HAMAP]
Taxonomic identifier156889 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus

Protein attributes

Sequence length270 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 270270Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290723

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane87 – 10721Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane147 – 16721Helical; Potential
Transmembrane193 – 21321Helical; Potential
Transmembrane223 – 24321Helical; Potential
Transmembrane250 – 27021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A0L9F4 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 514BC8C9936F327C

FASTA27029,193
        10         20         30         40         50         60 
MDLFNAAILA LIQGITEFLP ISSSGHLILT PYLLGWQDQG LVFDIAANSG SLAAVMLYFR 

        70         80         90        100        110        120 
REVGQMLRGG WRLLCAPRAW RQANAESHLV LQLALATIPV GLVGLACKDW VATVARDPMI 

       130        140        150        160        170        180 
IATTSILFGL LLWWADRQGR CNNDGSALSW RQVGIIGIAQ AFALIPGTSR SGVTMTAGLM 

       190        200        210        220        230        240 
LGLTREAAAR FSFLMAIPVG ILAALLDLKD LFAHPMQGDE LYFLGVGFCV SGLSAYMVIH 

       250        260        270 
GLLAWLKRQT MTPFVVYRVV LGVVIFATLG 

« Hide

References

[1]"Complete sequence of Magnetococcus sp. MC-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Goodwin L.A., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000471 Genomic DNA. Translation: ABK44597.1.
RefSeqYP_866003.1. NC_008576.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING156889.Mmc1_2096.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK44597; ABK44597; Mmc1_2096.
GeneID4480845.
KEGGmgm:Mmc1_2096.
PATRIC22430787. VBIMagSp23654_2139.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMASKTQIMF.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycMSP156889:GH36-2124-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_MAGSM
AccessionPrimary (citable) accession number: A0L9F4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: December 12, 2006
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families