SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0L8R9

- LPXB_MAGSM

UniProt

A0L8R9 - LPXB_MAGSM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Lipid-A-disaccharide synthase
Gene
lpxB, Mmc1_1854
Organism
Magnetococcus sp. (strain MC-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciMSP156889:GH36-1873-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthase (EC:2.4.1.182)
Gene namesi
Name:lpxB
Ordered Locus Names:Mmc1_1854
OrganismiMagnetococcus sp. (strain MC-1)
Taxonomic identifieri156889 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus
ProteomesiUP000002586: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 388388Lipid-A-disaccharide synthaseUniRule annotation
PRO_1000049404Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi156889.Mmc1_1854.

Structurei

3D structure databases

ProteinModelPortaliA0L8R9.

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018004.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

A0L8R9-1 [UniParc]FASTAAdd to Basket

« Hide

MGRPLRIAIV TGEASGDLLA ASLVSGLKKR FPRMQIYGIG GPRMKMLGLD    50
SMADAQELSI IGVVEVLNRF PRIRTIFNAL LKRLQSEPPD LLITVDLPDF 100
SLRMARKAKQ LGIPTVHYVS PQVWAWRSGR AKTIASYLDL LLCLFPFEPR 150
YYANTGLEAH FVGHPLVQEA VPSYSRSEAR KILGVSEAGQ LVAIMPGSRR 200
SEIQRLLETF LRTAERLWKR RTNLSFVLIQ AETISDQQLY EVWPEALRDL 250
PVIVRHGNAY NWLAASDALL VASGTATLEA ALIGIPMVVA YKVNPLTYQI 300
GKQLIKSKFI SLPNLIAQSA IVEERIQQDA NPEQLSEDLI QLLNRPQEAM 350
AMREALRVVK QSLLPPTHGA VEVVSDFILH KVGYRPGG 388
Length:388
Mass (Da):43,202
Last modified:December 12, 2006 - v1
Checksum:iD8469AF43AC08D7F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44362.1.
RefSeqiYP_865768.1. NC_008576.1.

Genome annotation databases

EnsemblBacteriaiABK44362; ABK44362; Mmc1_1854.
GeneIDi4481752.
KEGGimgm:Mmc1_1854.
PATRICi22430297. VBIMagSp23654_1903.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44362.1 .
RefSeqi YP_865768.1. NC_008576.1.

3D structure databases

ProteinModelPortali A0L8R9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 156889.Mmc1_1854.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK44362 ; ABK44362 ; Mmc1_1854 .
GeneIDi 4481752.
KEGGi mgm:Mmc1_1854.
PATRICi 22430297. VBIMagSp23654_1903.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018004.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci MSP156889:GH36-1873-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC-1.

Entry informationi

Entry nameiLPXB_MAGSM
AccessioniPrimary (citable) accession number: A0L8R9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3