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A0L8I1

- GCH4_MAGSM

UniProt

A0L8I1 - GCH4_MAGSM

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Protein

GTP cyclohydrolase FolE2

Gene
folE2, Mmc1_1766
Organism
Magnetococcus sp. (strain MC-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate By similarity.UniRule annotation

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei152 – 1521May be catalytically important By similarity

GO - Molecular functioni

  1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciMSP156889:GH36-1785-MONOMER.
UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2 (EC:3.5.4.16)
Gene namesi
Name:folE2
Ordered Locus Names:Mmc1_1766
OrganismiMagnetococcus sp. (strain MC-1)
Taxonomic identifieri156889 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus
ProteomesiUP000002586: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265GTP cyclohydrolase FolE2UniRule annotationPRO_0000289496Add
BLAST

Proteomic databases

PRIDEiA0L8I1.

Interactioni

Protein-protein interaction databases

STRINGi156889.Mmc1_1766.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1469.
HOGENOMiHOG000280679.
KOiK09007.
OrthoDBiEOG6X6RBH.

Family and domain databases

HAMAPiMF_01527_B. GTP_cyclohydrol_B.
InterProiIPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view]
PfamiPF02649. GCHY-1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00294. TIGR00294. 1 hit.

Sequencei

Sequence statusi: Complete.

A0L8I1-1 [UniParc]FASTAAdd to Basket

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MNNCQLPLSD VQSRQDHRRL DIDKVGVKNI RYPIVVKDRS VGSQSTTARI    50
NMYVNLPHQF KGTHMSRFLE VLAENQRAIS IENLPKLLKE VKQRLDAEEA 100
HIELDFPYFI TKKAPVSGVE ALMDYQVHFS GVMRGNAYQL TLTVEVPVTS 150
LCPCSKEISA YGAHNQRSHV KVSVQFSQFV WIEEVVDLVE RNASCELFTI 200
LKRPDEKFVT EKAYDNPKFV EDMVRDLADE LTHDPRISWF AVESENFESI 250
HNHSAYAFIE GGQRS 265
Length:265
Mass (Da):30,401
Last modified:May 5, 2009 - v2
Checksum:i48CABA82215BCE11
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44274.1.
RefSeqiYP_865680.1. NC_008576.1.

Genome annotation databases

EnsemblBacteriaiABK44274; ABK44274; Mmc1_1766.
GeneIDi4482592.
KEGGimgm:Mmc1_1766.
PATRICi22430115. VBIMagSp23654_1812.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44274.1 .
RefSeqi YP_865680.1. NC_008576.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 156889.Mmc1_1766.

Proteomic databases

PRIDEi A0L8I1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK44274 ; ABK44274 ; Mmc1_1766 .
GeneIDi 4482592.
KEGGi mgm:Mmc1_1766.
PATRICi 22430115. VBIMagSp23654_1812.

Phylogenomic databases

eggNOGi COG1469.
HOGENOMi HOG000280679.
KOi K09007.
OrthoDBi EOG6X6RBH.

Enzyme and pathway databases

UniPathwayi UPA00848 ; UER00151 .
BioCyci MSP156889:GH36-1785-MONOMER.

Family and domain databases

HAMAPi MF_01527_B. GTP_cyclohydrol_B.
InterProi IPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view ]
Pfami PF02649. GCHY-1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00294. TIGR00294. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC-1.

Entry informationi

Entry nameiGCH4_MAGSM
AccessioniPrimary (citable) accession number: A0L8I1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 5, 2009
Last modified: February 19, 2014
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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