ID   A0L7Z9_MAGMM            Unreviewed;       483 AA.
AC   A0L7Z9;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABK44092.1};
GN   OrderedLocusNames=Mmc1_1583 {ECO:0000313|EMBL:ABK44092.1};
OS   Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Magnetococcales;
OC   Magnetococcaceae; Magnetococcus.
OX   NCBI_TaxID=156889 {ECO:0000313|EMBL:ABK44092.1, ECO:0000313|Proteomes:UP000002586};
RN   [1] {ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=19465526; DOI=10.1128/AEM.02874-08;
RA   Schubbe S., Williams T.J., Xie G., Kiss H.E., Brettin T.S., Martinez D.,
RA   Ross C.A., Schuler D., Cox B.L., Nealson K.H., Bazylinski D.A.;
RT   "Complete genome sequence of the chemolithoautotrophic marine magnetotactic
RT   coccus strain MC-1.";
RL   Appl. Environ. Microbiol. 75:4835-4852(2009).
RN   [2] {ECO:0000313|EMBL:ABK44092.1, ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=22581902;
RA   Bazylinski D.A., Williams T.J., Lefevre C.T., Berg R.J., Zhang C.L.,
RA   Bowser S.S., Dean A.J., Beveridge T.J.;
RT   "Magnetococcus marinus gen. nov., sp. nov., a marine, magnetotactic
RT   bacterium that represents a novel lineage (Magnetococcaceae fam. nov.;
RT   Magnetococcales ord. nov.) at the base of the Alphaproteobacteria.";
RL   Int. J. Syst. Evol. Microbiol. 0:0-0(2012).
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC       {ECO:0000256|ARBA:ARBA00005381}.
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DR   EMBL; CP000471; ABK44092.1; -; Genomic_DNA.
DR   RefSeq; WP_011713241.1; NC_008576.1.
DR   AlphaFoldDB; A0L7Z9; -.
DR   STRING; 156889.Mmc1_1583; -.
DR   KEGG; mgm:Mmc1_1583; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG3850; Bacteria.
DR   HOGENOM; CLU_025433_2_1_5; -.
DR   OrthoDB; 9762462at2; -.
DR   Proteomes; UP000002586; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR048440; MASE10.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF20970; MASE10; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002586};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        191..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          211..263
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          301..433
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   483 AA;  53278 MW;  C6C7F03FF675DC1D CRC64;
     MDSSPQTGSI HLKLHALAGV AVLFLSFYGK QVCPFIDKVN FLHLFTTLST IAVVQIGLRV
     WMLRRFHKPS HGISPARQQF RLSVLNWLVT GVLACLVCWQ VYGTAFHWSS YLKLLVGYWA
     LGAGLLAQLE YILLEQHMRR FAHLGQGQER ITIRLLEAFA AFTIVPALVM TLISFRFVYE
     GYLARSAAFE VLFLAICFVG GALFVAWHYG RALHRDCTAL TEALQQVTQG HFGVRVDSSR
     ADELGSMAQG LNEMGQGLLL RERIRDAFGR FVNPQVADAF IQRFSQGEQA IQMGGERKEI
     TIMMADLRQF TPLSESLPPE ALTELLNSYL SVMVQVIQQH GGMIDKFIGD AILALFGLGH
     HDQPAQLQAV LAAQAMQVAL ADFNEKQRAK GAPTLNNGIG LHHGEVVAGY IGSTDRLEFT
     VIGHNVNMAA RIESMTKAPN PSLLFSQSVA DAVAHTLPVR QVTIATLKGI SEPIPLYTLA
     DPQ
//