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A0L7X6

- GCSPA_MAGSM

UniProt

A0L7X6 - GCSPA_MAGSM

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Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene
gcvPA, Mmc1_1560
Organism
Magnetococcus sp. (strain MC-1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine catabolic process Source: InterPro
  2. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciMSP156889:GH36-1577-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1 (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein subunit 1
Glycine decarboxylase subunit 1
Glycine dehydrogenase (aminomethyl-transferring) subunit 1
Gene namesi
Name:gcvPA
Ordered Locus Names:Mmc1_1560
OrganismiMagnetococcus sp. (strain MC-1)
Taxonomic identifieri156889 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus
ProteomesiUP000002586: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 461461Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotationPRO_1000045666Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits By similarity.

Protein-protein interaction databases

STRINGi156889.Mmc1_1560.

Structurei

3D structure databases

ProteinModelPortaliA0L7X6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0403.
HOGENOMiHOG000132025.
KOiK00282.
OMAiRLVGQTE.
OrthoDBiEOG6XWV3B.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
HAMAPiMF_00712. GcvPA.
InterProiIPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

A0L7X6-1 [UniParc]FASTAAdd to Basket

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MPFIPHTEDD VRLMLDTIGV ESIDALFDEI PAELNTHPIL ESVPKPQSEA    50
ATLRLQSARA REGDGRLNFI GAGAYEHHIP AAVWELVTRG EFYSAYTPYQ 100
AEASQGILQT IYEFQSMMAG LMGMDLSNAS LYDGATALAE AVLMAVRANP 150
APRGSTPRVI MPATVHPAYR EVVQTMVRHQ GIELVEPSFC AKRGGVAVSA 200
LNLYADEPVQ ALVIAQPNFF GQLEDVDFLT NWAHKRGALV IGVVNPVAMA 250
LLKPPAAWGE KGADIACGEG QPLGVPLSFG GPYLGFLSCR QALARQMPGR 300
IVGRTLDQEG KEGFVLTLQA REQHIRRAKA TSNICTNQGL LSIAATIHMA 350
MLGPEGLKNV ALTCHRRTQQ LWQRLALLEG VERCFEGPFF HEVAIKLSKP 400
AEEVLTCLSG VNIAGGYAVG RRYPGMENVL LVCCTETKER SDLDHYADAL 450
GLIMSEQGSA A 461
Length:461
Mass (Da):49,931
Last modified:December 12, 2006 - v1
Checksum:i0F80DA3E08AEBF74
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44069.1.
RefSeqiYP_865475.1. NC_008576.1.

Genome annotation databases

EnsemblBacteriaiABK44069; ABK44069; Mmc1_1560.
GeneIDi4484178.
KEGGimgm:Mmc1_1560.
PATRICi22429689. VBIMagSp23654_1600.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000471 Genomic DNA. Translation: ABK44069.1 .
RefSeqi YP_865475.1. NC_008576.1.

3D structure databases

ProteinModelPortali A0L7X6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 156889.Mmc1_1560.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK44069 ; ABK44069 ; Mmc1_1560 .
GeneIDi 4484178.
KEGGi mgm:Mmc1_1560.
PATRICi 22429689. VBIMagSp23654_1600.

Phylogenomic databases

eggNOGi COG0403.
HOGENOMi HOG000132025.
KOi K00282.
OMAi RLVGQTE.
OrthoDBi EOG6XWV3B.

Enzyme and pathway databases

BioCyci MSP156889:GH36-1577-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
HAMAPi MF_00712. GcvPA.
InterProi IPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 1 hit.
[Graphical view ]
PIRSFi PIRSF006815. GcvPA. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MC-1.

Entry informationi

Entry nameiGCSPA_MAGSM
AccessioniPrimary (citable) accession number: A0L7X6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: September 3, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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