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A0L7L5 (MUTS_MAGSM) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA mismatch repair protein MutS
Gene names
Name:mutS
Ordered Locus Names:Mmc1_1449
OrganismMagnetococcus sp. (strain MC-1) [Complete proteome] [HAMAP]
Taxonomic identifier156889 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaMagnetococcalesMagnetococcaceaeMagnetococcus

Protein attributes

Sequence length868 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity By similarity. HAMAP-Rule MF_00096

Sequence similarities

Belongs to the DNA mismatch repair MutS family.

Ontologies

Keywords
   Biological processDNA damage
DNA repair
   LigandATP-binding
DNA-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmismatch repair

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

damaged DNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

mismatched DNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 868868DNA mismatch repair protein MutS HAMAP-Rule MF_00096
PRO_0000335175

Regions

Nucleotide binding623 – 6308ATP Potential

Sequences

Sequence LengthMass (Da)Tools
A0L7L5 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: BABE88B54ADE10BA

FASTA86897,431
        10         20         30         40         50         60 
MSSPKQTPMI AQYLSIKAAH PETLLFFRMG DFYELFFDDA KQAAEALNIA LTSRGKSEGE 

        70         80         90        100        110        120 
PIPMAGIPVH ARQTYLNKLI EAGFKVAICE QMEPPGASKG PVRREVVRTV TPGTLTEESL 

       130        140        150        160        170        180 
LSPRENNYLV SYLPAAKRHP HALAALDLST GEFFALTLER EDQVAAELSR LEPAELLIPD 

       190        200        210        220        230        240 
NWEPEPWLKG WKRCLSRRGS WSFDGKEGAR VLLEHFQVTS LESFGVADSP PCLGVCGALL 

       250        260        270        280        290        300 
HYCRETQKEA LSHITGLSRL HQQEGMVLDE TCRRNLELNY NLKDGSRKSS LLGVMDRCIT 

       310        320        330        340        350        360 
PMGSRLLAQW INRPLQSLDA IATRQESVSW LRENLVAYQD LRERLRMVHD LERFLSRIAL 

       370        380        390        400        410        420 
RRASPRDLGG LRQTLQCLPQ LYAILTPADG HSLAVPSLLR ILADHFNGHE ALTKQLEQQL 

       430        440        450        460        470        480 
ADELPLNLKE GETIRLGFDQ TLDTLRSLSR DGKSYLTKLE VEEREKTGIP SLKIKYHRSF 

       490        500        510        520        530        540 
GYSMEVTKTH LDKVPPRYIQ RQTMTNGVRY VTEELKEYEE QLLTAEERML EREQLLFEAL 

       550        560        570        580        590        600 
AEQVARQAET LQASARAIAT LDVLANFAHI AEERNYCRPL LHEGAVIEIN QGRHPVVEQF 

       610        620        630        640        650        660 
SDTPFVANDI RLDNRQRTGL ITGPNMAGKS TLMRQVALIV LLAHTGACVP AGSAKIGRVD 

       670        680        690        700        710        720 
RIFTRVGASD DLAGGRSTFM VEMTETAHIL HHASERSLVI LDEIGRGTST YDGLSIAWAV 

       730        740        750        760        770        780 
AEHIHTQCQA RTLFATHYHE LTQLESQLDG VFNLTVEVKE WKDQILFLHT IVRGAADRSY 

       790        800        810        820        830        840 
GIHVAQLAGL PRAVTRRARE VLADLEEHAV HHPDSMGQGH APASQPYQLT LFEDAPPSPA 

       850        860 
LLELKRVDPD ELTPKEALEA LYRLKELL 

« Hide

References

[1]"Complete sequence of Magnetococcus sp. MC-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Goodwin L.A., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MC-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000471 Genomic DNA. Translation: ABK43958.1.
RefSeqYP_865364.1. NC_008576.1.

3D structure databases

ProteinModelPortalA0L7L5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING156889.Mmc1_1449.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK43958; ABK43958; Mmc1_1449.
GeneID4480625.
KEGGmgm:Mmc1_1449.
PATRIC22429469. VBIMagSp23654_1491.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0249.
HOGENOMHOG000221406.
KOK03555.
OMAGFGAHSL.
OrthoDBEOG6Q5NPV.

Enzyme and pathway databases

BioCycMSP156889:GH36-1465-MONOMER.

Family and domain databases

Gene3D3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_00096. MutS.
InterProIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR11361:SF34. PTHR11361:SF34. 1 hit.
PfamPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsTIGR01070. mutS1. 1 hit.
PROSITEPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMUTS_MAGSM
AccessionPrimary (citable) accession number: A0L7L5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 12, 2006
Last modified: April 16, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families