ID   A0L6N6_MAGMM            Unreviewed;       721 AA.
AC   A0L6N6;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABK43629.1};
GN   OrderedLocusNames=Mmc1_1112 {ECO:0000313|EMBL:ABK43629.1};
OS   Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Magnetococcales;
OC   Magnetococcaceae; Magnetococcus.
OX   NCBI_TaxID=156889 {ECO:0000313|EMBL:ABK43629.1, ECO:0000313|Proteomes:UP000002586};
RN   [1] {ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=19465526; DOI=10.1128/AEM.02874-08;
RA   Schubbe S., Williams T.J., Xie G., Kiss H.E., Brettin T.S., Martinez D.,
RA   Ross C.A., Schuler D., Cox B.L., Nealson K.H., Bazylinski D.A.;
RT   "Complete genome sequence of the chemolithoautotrophic marine magnetotactic
RT   coccus strain MC-1.";
RL   Appl. Environ. Microbiol. 75:4835-4852(2009).
RN   [2] {ECO:0000313|EMBL:ABK43629.1, ECO:0000313|Proteomes:UP000002586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC   {ECO:0000313|Proteomes:UP000002586};
RX   PubMed=22581902;
RA   Bazylinski D.A., Williams T.J., Lefevre C.T., Berg R.J., Zhang C.L.,
RA   Bowser S.S., Dean A.J., Beveridge T.J.;
RT   "Magnetococcus marinus gen. nov., sp. nov., a marine, magnetotactic
RT   bacterium that represents a novel lineage (Magnetococcaceae fam. nov.;
RT   Magnetococcales ord. nov.) at the base of the Alphaproteobacteria.";
RL   Int. J. Syst. Evol. Microbiol. 0:0-0(2012).
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DR   EMBL; CP000471; ABK43629.1; -; Genomic_DNA.
DR   RefSeq; WP_011712786.1; NC_008576.1.
DR   AlphaFoldDB; A0L6N6; -.
DR   STRING; 156889.Mmc1_1112; -.
DR   KEGG; mgm:Mmc1_1112; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   HOGENOM; CLU_000445_85_1_5; -.
DR   OrthoDB; 9789782at2; -.
DR   Proteomes; UP000002586; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002586};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        417..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          478..610
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   721 AA;  80060 MW;  48FBEC38FCC04BEB CRC64;
     MKRIRAIFLQ PKFWISFLLL MVLIIIQIVD PPLRQRLRLM SFDQLQQLSP RVYPEHLPLR
     VIAIDDASLQ SIGQWPWPRT RIAEIVAQLN AMGAQAIAFD MLFAEPDRTS PKQMMQNWPG
     QSALQTALAK LPDHDEIFAQ QIAQSSVVTG FVTASPATLA KDVSGQPQPK GGLFVFGGDI
     RTMLPDYQAA TVNLPLLEQA AEGNAVLELP ADTDGILRHL PLFYRIGSAT FPTLGLESIR
     LFLGLNQLAV TASAQDDALG PAGLRRLKLA SIERPITAAG EVFLHYRPLN PSRYISAAEL
     LKGKVEPALI ANHLVFIAAT SKGLGDTIFT PLKELVPGVE VHVQLTEQLI EGNYLQQPPL
     LDDKIVTGFI LFWLLLYTLL ARFRPVWAIL FVVAAMVGFA SYCWHLFSQQ QIFIDPLYPI
     LCMLLLFVST LIPQYLQLAK DERWVKDAFV RYVSPNRVKY LVENKDSLKL GGEERECSFV
     MTDLEGFTSL MEQYKPPTLV AMLNGYLDGM VSIAFQHEGT LDRIVGDAVA VLFSTPLPQA
     DHAARAIACA RDMDIFAQQF RQQQQAQGIP LGCTRIGVHT GRVIVGNFGG SKLLDYRALG
     DPINTAARLE SVNKHLGTRV CISVASVMQD ATFIGRPVGA LILKGKSQPL EVFEPLSQES
     YDSPQMQAYL AAYQQLQQGE SQAAKTFDDL LTRYPTDPLI QWHVKRLQQG QSGVEMTMSQ
     K
//