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A0L1S2 (SLMA_SHESA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nucleoid occlusion factor SlmA
Gene names
Name:slmA
Ordered Locus Names:Shewana3_3773
OrganismShewanella sp. (strain ANA-3) [Complete proteome] [HAMAP]
Taxonomic identifier94122 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length197 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions By similarity. HAMAP-Rule MF_01839

Subunit structure

Homodimer By similarity. Interacts with FtsZ By similarity. HAMAP-Rule MF_01839

Subcellular location

Cytoplasmnucleoid By similarity HAMAP-Rule MF_01839.

Sequence similarities

Belongs to the nucleoid occlusion factor SlmA family.

Contains 1 HTH tetR-type DNA-binding domain.

Ontologies

Keywords
   Biological processCell cycle
Cell division
   Cellular componentCytoplasm
   LigandDNA-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcell cycle

Inferred from electronic annotation. Source: UniProtKB-KW

cell division

Inferred from electronic annotation. Source: UniProtKB-KW

negative regulation of barrier septum assembly

Inferred from electronic annotation. Source: InterPro

   Cellular_componentbacterial nucleoid

Inferred from electronic annotation. Source: UniProtKB-HAMAP

cytoplasm

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 197197Nucleoid occlusion factor SlmA HAMAP-Rule MF_01839
PRO_1000070531

Regions

Domain7 – 6761HTH tetR-type
DNA binding30 – 4920H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
A0L1S2 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: FB1A71C69B72D5EE

FASTA19722,703
        10         20         30         40         50         60 
MAVSPKINRR EHILQCLAQM LETSPGQRIT TAKLASEVGV SEAALYRHFP SKARMFEGLI 

        70         80         90        100        110        120 
EFIEESLLSR INIIMNDEKD TMRRCQLVLQ LLLIFAERNP GISRVLNGDA LLGENERLRS 

       130        140        150        160        170        180 
RISTLFAKIE TQLKQILREK TLREGKGFNL DEAILANLLL AFAEGRIAQF VRSEFKLKPT 

       190 
QHFDEQWRFI QHQLLQS 

« Hide

References

[1]"Complete sequence of chromosome 1 of Shewanella sp. ANA-3."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Newman D., Salticov C., Konstantinidis K., Klappenback J., Tiedje J., Richardson P.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ANA-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000469 Genomic DNA. Translation: ABK49991.1.
RefSeqYP_871397.1. NC_008577.1.

3D structure databases

ProteinModelPortalA0L1S2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING94122.Shewana3_3773.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK49991; ABK49991; Shewana3_3773.
GeneID4479983.
KEGGshn:Shewana3_3773.
PATRIC23575590. VBISheSp134792_4150.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1309.
HOGENOMHOG000266053.
KOK05501.
OMAGERRVQI.
OrthoDBEOG6G7R3C.

Enzyme and pathway databases

BioCycSSP94122:GJ9K-3896-MONOMER.

Family and domain databases

Gene3D1.10.357.10. 1 hit.
HAMAPMF_01839. NO_factor_SlmA.
InterProIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR023769. NO_SlmA.
IPR015893. Tet_transcr_reg_TetR-like_C.
[Graphical view]
PfamPF00440. TetR_N. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSLMA_SHESA
AccessionPrimary (citable) accession number: A0L1S2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 12, 2006
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families