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Protein

Asparagine--tRNA ligase

Gene

asnS

Organism
Shewanella sp. (strain ANA-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSP94122:GJ9K-2399-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Asparagine--tRNA ligaseUniRule annotation (EC:6.1.1.22UniRule annotation)
Alternative name(s):
Asparaginyl-tRNA synthetaseUniRule annotation
Short name:
AsnRSUniRule annotation
Gene namesi
Name:asnSUniRule annotation
Ordered Locus Names:Shewana3_2306
OrganismiShewanella sp. (strain ANA-3)
Taxonomic identifieri94122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000002589 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Asparagine--tRNA ligasePRO_1000051426Add
BLAST

Proteomic databases

PRIDEiA0KXL6.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi94122.Shewana3_2306.

Structurei

3D structure databases

ProteinModelPortaliA0KXL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C5S. Bacteria.
COG0017. LUCA.
HOGENOMiHOG000226033.
KOiK01893.
OMAiPEDMEFF.
OrthoDBiPOG091H054V.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00534. Asn_tRNA_synth. 1 hit.
InterProiIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004522. Asn-tRNA-ligase.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
[Graphical view]
PANTHERiPTHR22594. PTHR22594. 2 hits.
PTHR22594:SF6. PTHR22594:SF6. 2 hits.
PfamiPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
[Graphical view]
PRINTSiPR01042. TRNASYNTHASP.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00457. asnS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0KXL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIASVASVF KGEHAVGSTV TVRGWVRTRR DSKAGISFLA VYDGSCFNPI
60 70 80 90 100
QGVVPNSLEN YDNEVLKLTA GCSVIVTGEI VESPGAGQAY ELQVTHVEVT
110 120 130 140 150
GWVEDPDTYP MAAKRHSIEH LRELAHLRPR TNIIGAVARV RNCLSQAIHR
160 170 180 190 200
FYHENGFVWV STPLITASDC EGAGEMFRVS TLDMENLPRT SDGKVDYDKD
210 220 230 240 250
FFGKEAFLTV SGQLNGETYA CALSKIYTFG PTFRAENSNT SRHLAEFWMV
260 270 280 290 300
EPEVAFATLS DIASLAEGML KYAFNAVLAE RMDDLQFFAQ HVDKTVIERL
310 320 330 340 350
QSFVSSDFAQ VDYTDAVDIL QKCGREFEFP VSWGIDLSSE HERYLAEEHF
360 370 380 390 400
KAPVVVKNYP KDIKAFYMRL NEDGKTVAAM DVLAPGIGEI IGGSQREERL
410 420 430 440 450
DVLDMRLEEM DLNKEDYWWY RDLRRYGTVP HSGFGLGFER LVSYVTGVSN
460
IRDVIPFPRA PRTANF
Length:466
Mass (Da):52,261
Last modified:December 12, 2006 - v1
Checksum:i1021A16EB1D9271F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000469 Genomic DNA. Translation: ABK48535.1.
RefSeqiWP_011717238.1. NC_008577.1.

Genome annotation databases

EnsemblBacteriaiABK48535; ABK48535; Shewana3_2306.
KEGGishn:Shewana3_2306.
PATRICi23572479. VBISheSp134792_2626.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000469 Genomic DNA. Translation: ABK48535.1.
RefSeqiWP_011717238.1. NC_008577.1.

3D structure databases

ProteinModelPortaliA0KXL6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi94122.Shewana3_2306.

Proteomic databases

PRIDEiA0KXL6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK48535; ABK48535; Shewana3_2306.
KEGGishn:Shewana3_2306.
PATRICi23572479. VBISheSp134792_2626.

Phylogenomic databases

eggNOGiENOG4105C5S. Bacteria.
COG0017. LUCA.
HOGENOMiHOG000226033.
KOiK01893.
OMAiPEDMEFF.
OrthoDBiPOG091H054V.

Enzyme and pathway databases

BioCyciSSP94122:GJ9K-2399-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00534. Asn_tRNA_synth. 1 hit.
InterProiIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004522. Asn-tRNA-ligase.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
[Graphical view]
PANTHERiPTHR22594. PTHR22594. 2 hits.
PTHR22594:SF6. PTHR22594:SF6. 2 hits.
PfamiPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
[Graphical view]
PRINTSiPR01042. TRNASYNTHASP.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00457. asnS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSYN_SHESA
AccessioniPrimary (citable) accession number: A0KXL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: September 7, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.