A0KV43 (G1091_SHESA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycosyl hydrolase family 109 protein 1
EC=3.2.1.-

Gene names

Ordered Locus Names:

Shewana3_1428

Organism

Shewanella sp. (strain ANA-3) [Complete proteome] [HAMAP]

Taxonomic identifier

94122 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Glycosidase By similarity.
Cofactor	Binds 1 NAD+ per subunit. The NAD cannot dissociate By similarity.
Post-translational modification	Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
Sequence similarities	Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

Ontologies

Keywords
Domain	Signal
Ligand	NAD
Molecular function	Glycosidase Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	oxidation-reduction process Inferred from electronic annotation. Source: GOC
Molecular_function	hydrolase activity, acting on glycosyl bonds Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 31	31	Tat-type signal Potential
	Chain	32 – 459	428	Glycosyl hydrolase family 109 protein 1		PRO_0000348563
Regions
	Nucleotide binding	64 – 65	2	NAD By similarity
	Nucleotide binding	135 – 138	4	NAD By similarity
	Nucleotide binding	155 – 156	2	NAD By similarity
	Region	244 – 247	4	Substrate binding By similarity
Sites
	Binding site	86	1	NAD By similarity
	Binding site	184	1	NAD By similarity
	Binding site	213	1	Substrate By similarity
	Binding site	232	1	Substrate By similarity
	Binding site	244	1	NAD By similarity
	Binding site	326	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0KV43 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 360BB310F4E3318D	FASTA	459	52,027
	10 20 30 40 50 60 MHNIHRRHFL KAAGAVTAGL VTANIALNAN ASSVAPKPRV GKSVIGLIAP KMELVRVGFI 70 80 90 100 110 120 GVGERGFSHV EQFCHLEGVE LKAICDTHQA VIDRAVEHIV KQNRPKPAVY TGNDLSYREL 130 140 150 160 170 180 LNRDDIDIVI ISTPWEWHAP MAIDTMESGK HAFVEVPLAL TVEECWQLVD TAERTQKNCM 190 200 210 220 230 240 MMENVNYGRE ELMVLNMVRQ GVFGELLHGE AAYIHELRWQ MKEIDHKTGS WRTYWHTKRN 250 260 270 280 290 300 GNLYPTHGLG PISQYMNINR GDRFDYLTSM SSPALGRALY AKREFPADHE RNQLKYINGD 310 320 330 340 350 360 MSTSLIKTVK GRTIMVQHDT TTPRPYSRHN LIQGTNGVFA GFPNRIAVEH GGFGKSYHEW 370 380 390 400 410 420 DMDMQKWYDK YDHPLWQRIG KEAEINGGHG GMDFVMLWRM VYCLRNGEAL DQDVYDGAAW 430 440 450 SVVNILSEQS LNNRSNSVNF PDFTRGAWEH ATPLGIVGA

References

[1]

"Complete sequence of chromosome 1 of Shewanella sp. ANA-3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Newman D., Salticov C., Konstantinidis K., Klappenback J., Tiedje J., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ANA-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000469 Genomic DNA. Translation: ABK47662.1.
RefSeq	YP_869068.1. NC_008577.1.
3D structure databases
ProteinModelPortal	A0KV43.
ModBase	Search...
Protein-protein interaction databases
STRING	94122.Shewana3_1428.
Protein family/group databases
CAZy	GH109. Glycoside Hydrolase Family 109.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABK47662; ABK47662; Shewana3_1428.
GeneID	4479645.
KEGG	shn:Shewana3_1428.
PATRIC	23570570. VBISheSp134792_1702.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0673.
HOGENOM	HOG000252553.
OMA	TGSWRTY.
ProtClustDB	CLSK901939.
Enzyme and pathway databases
BioCyc	SSP94122:GJ9K-1492-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 2 hits.
InterPro	IPR016040. NAD(P)-bd_dom. IPR000683. Oxidoreductase_N. IPR006311. TAT_signal. IPR019546. TAT_signal_bac_arc. [Graphical view]
Pfam	PF01408. GFO_IDH_MocA. 1 hit. PF10518. TAT_signal. 1 hit. [Graphical view]
TIGRFAMs	TIGR01409. TAT_signal_seq. 1 hit.
PROSITE	PS51318. TAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G1091_SHESA

Accession

Primary (citable) accession number: A0KV43

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	December 12, 2006
Last modified:	May 29, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program