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A0KV43 (G1091_SHESA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycosyl hydrolase family 109 protein 1

EC=3.2.1.-
Gene names
Ordered Locus Names:Shewana3_1428
OrganismShewanella sp. (strain ANA-3) [Complete proteome] [HAMAP]
Taxonomic identifier94122 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length459 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Glycosidase By similarity.

Cofactor

Binds 1 NAD+ per subunit. The NAD cannot dissociate By similarity.

Post-translational modification

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Sequence similarities

Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

Ontologies

Keywords
   DomainSignal
   LigandNAD
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionhydrolase activity, acting on glycosyl bonds

Inferred from electronic annotation. Source: UniProtKB-KW

oxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131Tat-type signal Potential
Chain32 – 459428Glycosyl hydrolase family 109 protein 1
PRO_0000348563

Regions

Nucleotide binding64 – 652NAD By similarity
Nucleotide binding135 – 1384NAD By similarity
Nucleotide binding155 – 1562NAD By similarity
Region244 – 2474Substrate binding By similarity

Sites

Binding site861NAD By similarity
Binding site1841NAD By similarity
Binding site2131Substrate By similarity
Binding site2321Substrate By similarity
Binding site2441NAD By similarity
Binding site3261Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
A0KV43 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 360BB310F4E3318D

FASTA45952,027
        10         20         30         40         50         60 
MHNIHRRHFL KAAGAVTAGL VTANIALNAN ASSVAPKPRV GKSVIGLIAP KMELVRVGFI 

        70         80         90        100        110        120 
GVGERGFSHV EQFCHLEGVE LKAICDTHQA VIDRAVEHIV KQNRPKPAVY TGNDLSYREL 

       130        140        150        160        170        180 
LNRDDIDIVI ISTPWEWHAP MAIDTMESGK HAFVEVPLAL TVEECWQLVD TAERTQKNCM 

       190        200        210        220        230        240 
MMENVNYGRE ELMVLNMVRQ GVFGELLHGE AAYIHELRWQ MKEIDHKTGS WRTYWHTKRN 

       250        260        270        280        290        300 
GNLYPTHGLG PISQYMNINR GDRFDYLTSM SSPALGRALY AKREFPADHE RNQLKYINGD 

       310        320        330        340        350        360 
MSTSLIKTVK GRTIMVQHDT TTPRPYSRHN LIQGTNGVFA GFPNRIAVEH GGFGKSYHEW 

       370        380        390        400        410        420 
DMDMQKWYDK YDHPLWQRIG KEAEINGGHG GMDFVMLWRM VYCLRNGEAL DQDVYDGAAW 

       430        440        450 
SVVNILSEQS LNNRSNSVNF PDFTRGAWEH ATPLGIVGA 

« Hide

References

[1]"Complete sequence of chromosome 1 of Shewanella sp. ANA-3."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Newman D., Salticov C., Konstantinidis K., Klappenback J., Tiedje J., Richardson P.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ANA-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000469 Genomic DNA. Translation: ABK47662.1.
RefSeqYP_869068.1. NC_008577.1.

3D structure databases

ProteinModelPortalA0KV43.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING94122.Shewana3_1428.

Protein family/group databases

CAZyGH109. Glycoside Hydrolase Family 109.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK47662; ABK47662; Shewana3_1428.
GeneID4479645.
KEGGshn:Shewana3_1428.
PATRIC23570570. VBISheSp134792_1702.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0673.
HOGENOMHOG000252553.
OMAMESGKHA.
OrthoDBEOG61P6MK.
ProtClustDBCLSK901939.

Enzyme and pathway databases

BioCycSSP94122:GJ9K-1492-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 2 hits.
InterProIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PfamPF01408. GFO_IDH_MocA. 1 hit.
PF10518. TAT_signal. 1 hit.
[Graphical view]
TIGRFAMsTIGR01409. TAT_signal_seq. 1 hit.
PROSITEPS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG1091_SHESA
AccessionPrimary (citable) accession number: A0KV43
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: December 12, 2006
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries