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A0KUF0

- GLSA_SHESA

UniProt

A0KUF0 - GLSA_SHESA

Protein

Glutaminase

Gene

glsA

Organism
Shewanella sp. (strain ANA-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei63 – 631SubstrateUniRule annotation
    Binding sitei114 – 1141SubstrateUniRule annotation
    Binding sitei158 – 1581SubstrateUniRule annotation
    Binding sitei165 – 1651SubstrateUniRule annotation
    Binding sitei189 – 1891SubstrateUniRule annotation
    Binding sitei240 – 2401SubstrateUniRule annotation
    Binding sitei258 – 2581Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciSSP94122:GJ9K-1232-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:Shewana3_1184
    OrganismiShewanella sp. (strain ANA-3)
    Taxonomic identifieri94122 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000002589: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 304304GlutaminasePRO_1000048360Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi94122.Shewana3_1184.

    Structurei

    3D structure databases

    ProteinModelPortaliA0KUF0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiMSIAVWS.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A0KUF0-1 [UniParc]FASTAAdd to Basket

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    MPEQALLEEV VDKVRPLLGQ GKVANYIPAL ANVDAGKLGI AVTTIDGETI    50
    GAGDYLEPFS IQSISKVFSL TLALTLYEET EIWSRVGKEP SGHSFNSLVQ 100
    VELERGKPRN PFINAGALVI ADLLQSRLGA PKHRMLELVR ALSQNDKVCF 150
    DKQVADSEYQ HSARNAAIAY LMKSFGNFQG DVDTVLRTYF HYCALKMNCA 200
    DLSRAMLYLA NRGKTLDGTE LISQVQTRQL NALLATSGLY DGAGEFAYRV 250
    GMPGKSGVGG GIIAVIPGEL SVCVWSPELD NQGNSLAGTA MLEHLSQRLG 300
    RSIF 304
    Length:304
    Mass (Da):32,925
    Last modified:December 12, 2006 - v1
    Checksum:i40DD255431CEECD4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000469 Genomic DNA. Translation: ABK47419.1.
    RefSeqiYP_868825.1. NC_008577.1.

    Genome annotation databases

    EnsemblBacteriaiABK47419; ABK47419; Shewana3_1184.
    GeneIDi4478701.
    KEGGishn:Shewana3_1184.
    PATRICi23570048. VBISheSp134792_1457.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000469 Genomic DNA. Translation: ABK47419.1 .
    RefSeqi YP_868825.1. NC_008577.1.

    3D structure databases

    ProteinModelPortali A0KUF0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 94122.Shewana3_1184.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK47419 ; ABK47419 ; Shewana3_1184 .
    GeneIDi 4478701.
    KEGGi shn:Shewana3_1184.
    PATRICi 23570048. VBISheSp134792_1457.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi MSIAVWS.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci SSP94122:GJ9K-1232-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ANA-3.

    Entry informationi

    Entry nameiGLSA_SHESA
    AccessioniPrimary (citable) accession number: A0KUF0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3