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Protein

Glutaminase

Gene

glsA

Organism
Shewanella sp. (strain ANA-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei63SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1
Binding sitei158SubstrateUniRule annotation1
Binding sitei165SubstrateUniRule annotation1
Binding sitei189SubstrateUniRule annotation1
Binding sitei240SubstrateUniRule annotation1
Binding sitei258Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:Shewana3_1184
OrganismiShewanella sp. (strain ANA-3)
Taxonomic identifieri94122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000002589 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000483601 – 304GlutaminaseAdd BLAST304

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi94122.Shewana3_1184.

Structurei

3D structure databases

ProteinModelPortaliA0KUF0.
SMRiA0KUF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiEPSGNPF.
OrthoDBiPOG091H02PU.

Family and domain databases

HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiView protein in InterPro
IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiView protein in Pfam
PF04960. Glutaminase. 1 hit.
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A0KUF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEQALLEEV VDKVRPLLGQ GKVANYIPAL ANVDAGKLGI AVTTIDGETI
60 70 80 90 100
GAGDYLEPFS IQSISKVFSL TLALTLYEET EIWSRVGKEP SGHSFNSLVQ
110 120 130 140 150
VELERGKPRN PFINAGALVI ADLLQSRLGA PKHRMLELVR ALSQNDKVCF
160 170 180 190 200
DKQVADSEYQ HSARNAAIAY LMKSFGNFQG DVDTVLRTYF HYCALKMNCA
210 220 230 240 250
DLSRAMLYLA NRGKTLDGTE LISQVQTRQL NALLATSGLY DGAGEFAYRV
260 270 280 290 300
GMPGKSGVGG GIIAVIPGEL SVCVWSPELD NQGNSLAGTA MLEHLSQRLG

RSIF
Length:304
Mass (Da):32,925
Last modified:December 12, 2006 - v1
Checksum:i40DD255431CEECD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000469 Genomic DNA. Translation: ABK47419.1.
RefSeqiWP_011621971.1. NC_008577.1.

Genome annotation databases

EnsemblBacteriaiABK47419; ABK47419; Shewana3_1184.
KEGGishn:Shewana3_1184.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiGLSA_SHESA
AccessioniPrimary (citable) accession number: A0KUF0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: June 7, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families