A0KU09 (DEOB_SHESA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphopentomutase
EC=5.4.2.7

Alternative name(s):
Phosphodeoxyribomutase

Gene names

Name:	deoB
Ordered Locus Names:	Shewana3_1043

Organism

Shewanella sp. (strain ANA-3) [Complete proteome] [HAMAP]

Taxonomic identifier

94122 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphotransfer between the C1 and C5 carbon atoms of pentose By similarity. HAMAP-Rule MF_00740
Catalytic activity	Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate. HAMAP-Rule MF_00740 2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate. HAMAP-Rule MF_00740
Cofactor	Binds 1 or 2 manganese ions Potential.
Pathway	Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3. HAMAP-Rule MF_00740
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the phosphopentomutase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	5-phosphoribose 1-diphosphate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway cellular metabolic compound salvage Inferred from electronic annotation. Source: InterPro deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: HAMAP phosphopentomutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 404	404	Phosphopentomutase HAMAP-Rule MF_00740		PRO_1000046400
Sites
	Metal binding	10	1	Manganese By similarity
	Metal binding	308	1	Manganese By similarity
	Metal binding	344	1	Manganese By similarity
	Metal binding	345	1	Manganese By similarity
	Metal binding	356	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0KU09 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 9035DE1B0BD3122E	FASTA	404	43,596
	10 20 30 40 50 60 MKRTVIMMLD SFGVGAAGDA AKFGDLGSDT FGHIAKACAE GEADIGREGP LTLPNLARLG 70 80 90 100 110 120 LAHAAMESTG AFAPGFADNV ELIGAYGHAQ ELSSGKDTPS GHWEMAGVPV LFEWGYFSEH 130 140 150 160 170 180 QNSFPKELTD KILARAGLDG FLGNCHASGT TILEELGEEH MRSGKPIFYT SADSVFQIAC 190 200 210 220 230 240 HEGTFGLENL YRLCEIAREE LEPYNIGRVI ARPFDGTGPS DFARTGNRKD YSLEPPAKTV 250 260 270 280 290 300 LDKLKAAGGE VVSVGKIADI YAYCGITKKV KANGLEALFD ATLAEVKSAG ENTIVFTNFV 310 320 330 340 350 360 DFDSHYGHRR DVAGYAKGLE YFDSRLPEML ALLDEDDLLI LTADHGCDPT WQGTDHTREY 370 380 390 400 VPVLAYGAGL KAGSLGRRNS FADIGQSIAS YFKLEPMEYG ESFI

References

[1]

"Complete sequence of chromosome 1 of Shewanella sp. ANA-3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Newman D., Salticov C., Konstantinidis K., Klappenback J., Tiedje J., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ANA-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000469 Genomic DNA. Translation: ABK47278.1.
RefSeq	YP_868684.1. NC_008577.1.
3D structure databases
ProteinModelPortal	A0KU09.
ModBase	Search...
Protein-protein interaction databases
STRING	94122.Shewana3_1043.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABK47278; ABK47278; Shewana3_1043.
GeneID	4479388.
KEGG	shn:Shewana3_1043.
PATRIC	23569726. VBISheSp134792_1308.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1015.
HOGENOM	HOG000008159.
KO	K01839.
OMA	PNMAKLG.
ProtClustDB	PRK05362.
Enzyme and pathway databases
UniPathway	UPA00087; UER00173.
Family and domain databases
Gene3D	3.30.70.1250. 1 hit. 3.40.720.10. 2 hits.
HAMAP	MF_00740. Phosphopentomut.
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR010045. DeoB. IPR006124. Metalloenzyme. IPR024052. Phosphopentomutase_DeoB_cap. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. [Graphical view]
PIRSF	PIRSF001491. Ppentomutase. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit. SSF143856. SSF143856. 1 hit.
TIGRFAMs	TIGR01696. deoB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOB_SHESA

Accession

Primary (citable) accession number: A0KU09

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program